Vitamin d3 and Questran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin d3 (cholecalciferol) and Questran (cholestyramine). Common drug interactions include bronchitis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin d3 and Questran. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,171 Vitamin d3 users. Check the latest studies of Vitamin d3.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.



On Jul, 25, 2026

34 people who take Vitamin d3 and Questran together, and have interactions are studied.

Vitamin d3 and Questran drug interactions.

What are the common drug interactions of Vitamin D3 and Questran, by gender? *:

female:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Cheilitis (infection of lips)
  3. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  4. Confusional state
  5. Cystic fibrosis (disease of the secretary glands)
  6. Cystitis (inflammation of the wall of the bladder)
  7. Decreased appetite
  8. Haematocrit decreased
  9. Haemoglobin decreased
  10. Haemorrhage (bleeding)

male:

  1. Fatigue (feeling of tiredness)
  2. Cough
  3. Pain
  4. Platelet count increased
  5. Pneumonia
  6. Thrombocytopenia (decrease of platelets in blood)
  7. Abdominal discomfort
  8. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  9. Acute respiratory failure
  10. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

What are the common drug interactions of Vitamin D3 and Questran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Migraine (headache)
  2. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)

30-39:

  1. Osteopenia (a condition where bone mineral density is lower than normal)
  2. Pancreatic insufficiency
  3. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  4. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  5. Splenic artery aneurysm (enlargement of splenic artery)
  6. Staphylococcal infection (an infection with staphylococcus bacteria)
  7. Tumour marker increased
  8. White blood cell count increased
  9. Fatigue (feeling of tiredness)
  10. Abdominal discomfort

40-49:

  1. Blood pressure increased
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  4. Muscle spasms (muscle contraction)
  5. Myalgia (muscle pain)
  6. Nervousness
  7. Oedema peripheral (superficial swelling)
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  9. Urinary tract disorder

50-59:

  1. Anxiety
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Cough
  4. Dyspnoea (difficult or laboured respiration)
  5. Fatigue (feeling of tiredness)
  6. Haematocrit increased
  7. Hyperhidrosis (abnormally increased sweating)
  8. Iron deficiency
  9. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  10. Pain

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Nausea (feeling of having an urge to vomit)
  3. Erythema (redness of the skin)
  4. Faeces discoloured
  5. Fatigue (feeling of tiredness)
  6. Flatulence (flatus expelled through the anus)
  7. Gait disturbance
  8. Glossodynia (a burning or painful sensation in the tongue)
  9. Insomnia (sleeplessness)
  10. Intestinal obstruction

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 17.65%
  2. High Blood Pressure: 5 people, 14.71%
  3. Depression: 5 people, 14.71%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 11.76%
  5. Multiple Myeloma (cancer of the plasma cells): 4 people, 11.76%
  6. Stress And Anxiety: 3 people, 8.82%
  7. Pain: 3 people, 8.82%
  8. High Blood Cholesterol: 3 people, 8.82%
  9. Renal Cell Carcinoma (a kidney cancer): 2 people, 5.88%
  10. Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin d3 and Questran?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin d3 and Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin d3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin d3 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Questran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cholecalciferol and cholestyramine (the active ingredients of Vitamin d3 and Questran, respectively), and Vitamin d3 and Questran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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