Vitamin e and Mysoline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin e (tocopherols and tocotrienols) and Mysoline (primidone). Common drug interactions include disorientation among females and obsessive-compulsive disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin e and Mysoline. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Mysoline?

Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.

On Jul, 15, 2026

57 people who take Vitamin e and Mysoline together, and have interactions are studied.

Vitamin e and Mysoline drug interactions.

What are the common drug interactions of Vitamin E and Mysoline, by gender? *:

female:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug exposure during pregnancy
Drug level above therapeutic
Dysarthria (speech disorder)
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspepsia (indigestion)
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gait disturbance

male:

Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Pathological gambling
Asthenia (weakness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Confusion
Confusional state
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dehydration (dryness resulting from the removal of water)
Drug level increased
Drug toxicity

What are the common drug interactions of Vitamin E and Mysoline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anticonvulsant drug level increased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Colitis (inflammation of colon)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dizziness
Drug exposure during pregnancy
Drug ineffective
Hypotension (abnormally low blood pressure)

50-59:

Headache (pain in head)

60+:

Fall
Foot fracture
Headache (pain in head)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Febrile neutropenia (fever with reduced white blood cells)
Hyperventilation
Nausea (feeling of having an urge to vomit)
Pigmentation disorder (disturbances of human skin colour)
Pruritus (severe itching of the skin)
Respiratory alkalosis (elevated blood ph due to excess breathing)

What are the existing conditions these people have? *

Pain: 10 people, 17.54%
Hypersensitivity: 6 people, 10.53%
Constipation: 6 people, 10.53%
Dizziness: 6 people, 10.53%
Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 10.53%
Sleep Disorder: 6 people, 10.53%
Bone Disorder: 6 people, 10.53%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 10.53%
Rickets (softening of bones): 6 people, 10.53%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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