Vraylar and Prednisone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vraylar (cariprazine hydrochloride) and Prednisone (prednisone). Common drug interactions include proteinuria among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Vraylar and Prednisone. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Vraylar?

Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

57 people who take Vraylar and Prednisone together, and have interactions are studied.

Vraylar and Prednisone drug interactions.

What are the common drug interactions of Vraylar and Prednisone, by gender? *:

female:

Proteinuria (presence of protein in the urine)
Pyrexia (fever)
Rash pruritic (redness with itching)
Renal tubular necrosis (death of kidney tubules)
Seasonal allergy (allergic condition due to certain season)
Sleep disorder
Drug ineffective
Memory impairment
Malaise (a feeling of general discomfort or uneasiness)
Constipation

male:

Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Liver injury
Osteopenia (a condition where bone mineral density is lower than normal)
Abnormal dreams
Chronic kidney disease
Depression
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)

What are the common drug interactions of Vraylar and Prednisone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dizziness
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Pruritus (severe itching of the skin)
Psoriasis (immune-mediated disease that affects the skin)
Throat irritation

30-39:

Psoriasis (immune-mediated disease that affects the skin)
Drug ineffective
Depression
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Fall
Foot fracture
Ligament rupture (tear in ligament)
Memory impairment
Abnormal dreams
Adrenal disorder

40-49:

Chronic kidney disease
Arthralgia (joint pain)
Depression
Knee arthroplasty
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Nausea (feeling of having an urge to vomit)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Post procedural infection
Suicidal ideation

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Bone density decreased
Multiple fractures
Renal failure (kidney dysfunction)
Osteopenia (a condition where bone mineral density is lower than normal)
Chronic kidney disease
Hospitalisation

60+:

Drug ineffective
Memory impairment
Pruritus (severe itching of the skin)
Swelling face
Fatigue (feeling of tiredness)
Asthenia (weakness)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Disease progression
Fall

What are the existing conditions these people have? *

Pain: 9 people, 15.79%
Hypersensitivity: 8 people, 14.04%
Stress And Anxiety: 7 people, 12.28%
High Blood Cholesterol: 7 people, 12.28%
Bipolar Disorder (mood disorder): 6 people, 10.53%
Depression: 6 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 10.53%
High Blood Pressure: 5 people, 8.77%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 8.77%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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