Vx-950 and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vx-950 (telaprevir) and Profen (ibuprofen). Common drug interactions include anorectal discomfort among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Vx-950 and Profen. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Vx-950?

Vx-950 has active ingredients of telaprevir. eHealthMe is studying from 9,465 Vx-950 users. Check the latest studies of Vx-950.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 12, 2026

99 people who take Vx-950 and Profen together, and have interactions are studied.

What are the common drug interactions of Vx-950 and Profen, by gender? *:

female:

Anorectal discomfort
Headache (pain in head)
Pruritus (severe itching of the skin)
Dysgeusia (disorder of the sense of taste)
Vision blurred
Chills (felling of cold)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Influenza like illness
Insomnia (sleeplessness)
Pyrexia (fever)

male:

Fatigue (feeling of tiredness)
Anorectal discomfort
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Insomnia (sleeplessness)
Chest pain
Anal pruritus (anal itching)
Dizziness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Rash

What are the common drug interactions of Vx-950 and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Pancreatitis (inflammation of pancreas)
Pruritus (severe itching of the skin)
Rash
Anal pruritus (anal itching)
Diarrhoea
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Influenza like illness

30-39:

Anaemia (lack of blood)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Chest pain
Diarrhoea
Anorectal discomfort
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Decreased appetite
Haematochezia (passage of stools containing blood)
Headache (pain in head)

40-49:

Hyperbilirubinaemia (excess of bilirubin in the blood)
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Anorectal discomfort
Fatigue (feeling of tiredness)
Influenza like illness
Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

50-59:

Appetite disorder (abnormal eating habits)
Arthralgia (joint pain)
Bone disorder
Bone marrow failure
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Disturbance in attention
Dry mouth
Eye irritation
Feeling hot

60+:

Liver disorder (liver diseases)
Tibia fracture (fracture of lower leg bone)
Vomiting
Abscess soft tissue (soft tissue abscesses)
Comminuted fracture (bone has broken into several pieces)
Dysstasia (difficulty in standing)
Fall
Femur fracture
Fibula fracture
Fracture nonunion (permanent failure of healing following a broken bone)

What are the existing conditions these people have? *

Hepatitis C: 97 people, 97.98%
Hiv Infection: 17 people, 17.17%
Depression: 11 people, 11.11%
Muscle Aches (muscle pain): 10 people, 10.10%
Rashes (redness): 7 people, 7.07%
Insomnia (sleeplessness): 7 people, 7.07%
Diabetes: 7 people, 7.07%
Stress And Anxiety: 6 people, 6.06%
Nausea (feeling of having an urge to vomit): 5 people, 5.05%
Headache (pain in head): 5 people, 5.05%

* Approximation only. Some reports may have incomplete information.

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