Xanax and Ifosfamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xanax (alprazolam) and Ifosfamide (ifosfamide). Common drug interactions include chills among females and encephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Xanax and Ifosfamide. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,340 Xanax users. Check the latest studies of Xanax.

What is Ifosfamide?

Ifosfamide has active ingredients of ifosfamide. eHealthMe is studying from 21,285 Ifosfamide users. Check the latest studies of Ifosfamide.



On Jan, 04, 2026

36 people who take Xanax and Ifosfamide together, and have interactions are studied.

Xanax and Ifosfamide drug interactions.

What are the common drug interactions of Xanax and Ifosfamide, by gender? *:

female:

  1. Chills (felling of cold)
  2. Confusional state
  3. Depression
  4. Disease progression
  5. Dizziness
  6. Emotional distress
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Fibrin d dimer increased
  9. Flushing (the warm, red condition of human skin)
  10. Gingival pain (gum pain)

male:

  1. Encephalopathy (functioning of the brain is affected by some agent or condition)
  2. Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
  3. Dystonia (abnormal muscle tone)
  4. Epistaxis (bleed from the nose)
  5. Gingival bleeding (bleeding gums)
  6. Pancreatitis acute (sudden inflammation of pancreas)
  7. Bacterial translocation
  8. Bone marrow failure
  9. Enterobacter bacteraemia (enterobacter cloacae are nosocomial pathogens that can cause a range of infections such as bacteraemia, lower respiratory tract infection, skin)
  10. Pyelocaliectasis

What are the common drug interactions of Xanax and Ifosfamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
  2. Mucosal inflammation (infection of mucous membrane)
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Epistaxis (bleed from the nose)
  5. Gingival bleeding (bleeding gums)

10-19:

  1. Acute respiratory distress syndrome
  2. Encephalopathy (functioning of the brain is affected by some agent or condition)
  3. Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
  4. Mucosal inflammation (infection of mucous membrane)
  5. Pulmonary embolism (blockage of the main artery of the lung)

20-29:

  1. Angioedema (rapid swelling of the dermis)
  2. Dystonia (abnormal muscle tone)

30-39:

  1. Renal tubular disorder (disease of kidney tubules)

40-49:

  1. Delirium (wild excitement)
  2. Depression
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Dizziness
  5. Electrocardiogram qt corrected interval prolonged
  6. Electrocardiogram qt prolonged
  7. Electrocardiogram qt shortened
  8. Emotional distress
  9. Gastrointestinal ulcer
  10. Hallucination (an experience involving the perception of something not present)

50-59:

  1. Encephalopathy (functioning of the brain is affected by some agent or condition)
  2. Pneumonia
  3. Abdominal pain
  4. Activated partial thromboplastin time prolonged
  5. Anaemia (lack of blood)
  6. Blood amylase increased
  7. Blood creatinine decreased
  8. Blood glucose increased
  9. Blood lactic acid decreased
  10. Blood phosphorus decreased

60+:

  1. Encephalopathy (functioning of the brain is affected by some agent or condition)
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  3. Platelet count decreased
  4. White blood cell count decreased
  5. Anaphylactic reaction (serious allergic reaction)
  6. Angioedema (rapid swelling of the dermis)
  7. Aplasia (defective development or congenital absence of an organ or tissue)
  8. Blood immunoglobulin e increased
  9. Delirium (wild excitement)
  10. Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 19.44%
  2. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 5 people, 13.89%
  3. Pain: 5 people, 13.89%
  4. Testicular Neoplasm (testes tumour): 4 people, 11.11%
  5. Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 11.11%
  6. Neuralgia (pain in one or more nerves): 4 people, 11.11%
  7. Dyslipidaemia (abnormal amount of lipids): 4 people, 11.11%
  8. Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 3 people, 8.33%
  9. Ewing's Sarcoma (malignant small, round, blue cell tumour): 3 people, 8.33%
  10. Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xanax and Ifosfamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xanax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ifosfamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xanax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ifosfamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on alprazolam and ifosfamide (the active ingredients of Xanax and Ifosfamide, respectively), and Xanax and Ifosfamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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