Xigris and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xigris (drotrecogin alfa (activated)) and Morphine sulfate (morphine sulfate). Common drug interactions include haematocrit decreased among females and haematocrit decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Xigris and Morphine sulfate. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Xigris?

Xigris has active ingredients of drotrecogin alfa (activated). eHealthMe is studying from 3,542 Xigris users. Check the latest studies of Xigris.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,262 Morphine sulfate users. Check the latest studies of Morphine sulfate.

On Aug, 04, 2026

22 people who take Xigris and Morphine sulfate together, and have interactions are studied.

Xigris and Morphine sulfate drug interactions.

What are the common drug interactions of Xigris and Morphine Sulfate, by gender? *:

female:

Haematocrit decreased
Activated partial thromboplastin time prolonged
Haemoglobin decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Atelectasis (partial or complete collapse of the lung)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
International normalised ratio increased
Pancreatitis (inflammation of pancreas)

male:

Haematocrit decreased
Haemoglobin decreased
Blood creatine increased
Blood creatinine increased
Blood fibrinogen increased
Catheter site haemorrhage (bleeding at catheter site)
Disease recurrence
Drug ineffective
Fibrin d dimer increased
Fungal infection

What are the common drug interactions of Xigris and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Leukocytosis (increased white blood cells)
Multi-organ failure (multisystem organ failure)
Organ failure
Pleural effusion (water on the lungs)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
White blood cell count increased
Atelectasis (partial or complete collapse of the lung)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pancreatitis (inflammation of pancreas)

40-49:

Activated partial thromboplastin time prolonged
Blood urea increased
Faecal occult blood positive
Haematocrit decreased
Haemoglobin decreased
Platelet count decreased
White blood cell count increased
Bacterial infection
Blood creatine increased
Blood creatinine increased

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Cardiac arrest
Hepatic enzyme increased
Infusion site reaction
Platelet count decreased
Protein total decreased
Rash generalised (rash on most of body parts)
Thrombocythaemia (an increased number of platelets in the circulating blood)

60+:

Haematocrit decreased
Haemoglobin decreased
Acute respiratory failure
Blood bicarbonate decreased
Blood creatinine increased
Blood fibrinogen increased
Blood ph decreased
Blood pressure fluctuation
Bronchial hyperreactivity
Candidiasis (candidiasis or thrush is a fungal infection)

What are the existing conditions these people have? *

Sepsis (a severe blood infection that can lead to organ failure and death): 18 people, 81.82%

* Approximation only. Some reports may have incomplete information.

Do you take Xigris and Morphine sulfate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously