Xtandi and Oxycodone and acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xtandi (enzalutamide) and Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride). Common drug interactions include fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Xtandi and Oxycodone and acetaminophen. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Xtandi?

Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

71 people who take Xtandi and Oxycodone and acetaminophen together, and have interactions are studied.

Xtandi and Oxycodone and acetaminophen drug interactions.

What are the common drug interactions of Xtandi and Oxycodone And Acetaminophen, by gender? *:

female:

n/a

male:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Head discomfort
Kidney infection
Vomiting
Pain in extremity
Drug ineffective
Death
Haemorrhage (bleeding)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Xtandi and Oxycodone And Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal distension
Decreased appetite
Exostosis (formation of new bone on the surface of a bone)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Hypophagia (reduced food intake)
Nausea (feeling of having an urge to vomit)
Pain in extremity

60+:

Asthenia (weakness)
Peripheral swelling
Influenza
Muscular weakness (muscle weakness)
Vomiting
Arthralgia (joint pain)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Productive cough
Rhinorrhoea (watery mucus discharge from the nose)

What are the existing conditions these people have? *

Prostate Cancer: 27 people, 38.03%
Prostate Cancer Stage Iv: 4 people, 5.63%
Prostate Cancer Metastatic: 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

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