Xtandi and Sodium bicarbonate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xtandi (enzalutamide) and Sodium bicarbonate (sodium bicarbonate). Common drug interactions include fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Xtandi and Sodium bicarbonate. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Xtandi?

Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.



On Jul, 09, 2026

49 people who take Xtandi and Sodium bicarbonate together, and have interactions are studied.

Xtandi and Sodium bicarbonate drug interactions.

What are the common drug interactions of Xtandi and Sodium Bicarbonate, by gender? *:

female:

n/a

male:

  1. Fatigue (feeling of tiredness)
  2. Death
  3. Hallucination (an experience involving the perception of something not present)
  4. Lip dry
  5. Nausea (feeling of having an urge to vomit)
  6. Thermal burn (burn by heat)
  7. Asthenia (weakness)
  8. Headache (pain in head)
  9. Prostatic specific antigen increased
  10. Malignant neoplasm progression (cancer tumour came back)

What are the common drug interactions of Xtandi and Sodium Bicarbonate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Fatigue (feeling of tiredness)
  2. Hot flush (sudden feelings of heat)
  3. Headache (pain in head)
  4. Drug ineffective
  5. Death
  6. Dysgeusia (disorder of the sense of taste)
  7. Nausea (feeling of having an urge to vomit)
  8. Malignant neoplasm progression (cancer tumour came back)
  9. Prostatic specific antigen increased
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Prostate Cancer: 24 people, 48.98%
  2. Metastases To Bone (cancer spreads to bone): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Xtandi and Sodium bicarbonate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xtandi and Sodium bicarbonate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xtandi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sodium bicarbonate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xtandi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sodium bicarbonate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enzalutamide and sodium bicarbonate (the active ingredients of Xtandi and Sodium bicarbonate, respectively), and Xtandi and Sodium bicarbonate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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