Yasmin and Ovral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Yasmin (drospirenone; ethinyl estradiol) and Ovral (ethinyl estradiol; norgestrel). Common drug interactions include gallbladder cholesterolosis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Yasmin and Ovral. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Yasmin?

Yasmin has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 48,855 Yasmin users. Check the latest studies of Yasmin.

What is Ovral?

Ovral has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 1,571 Ovral users. Check the latest studies of Ovral.

On Jul, 17, 2026

49 people who take Yasmin and Ovral together, and have interactions are studied.

What are the common drug interactions of Yasmin and Ovral, by gender? *:

female:

Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Hemiplegia (paralysis of one side of the body)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Influenza like illness
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Irritability
Loss of libido (loss of sexual urge)
Lymphadenopathy (disease or enlargement of lymph nodes)
Myalgia (muscle pain)

male:

Pain
Injury
Cholecystitis (infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Drug exposure during pregnancy
Drug ineffective
Gallbladder disorder
Metrorrhagia (uterine bleeding at irregular intervals)
Mitral valve disease (disease of mitral valve of heart)

What are the common drug interactions of Yasmin and Ovral, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cholecystitis (infection of gallbladder)
Pain
Injury
Metrorrhagia (uterine bleeding at irregular intervals)
Abdominal pain
Nausea (feeling of having an urge to vomit)
Anxiety
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain upper

20-29:

Pancreatic cyst
Pancreatic neuroendocrine tumour
Peritoneal cyst
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Urinary tract infection
Diarrhoea
Drug tolerance decreased
Dysaesthesia (abnormal sensation)
Dyspnoea (difficult or laboured respiration)
Facial pain

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pain
Injury
Pulmonary embolism (blockage of the main artery of the lung)
Anxiety
Emotional distress
Pain in extremity
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
General physical health deterioration (weak health status)
Local swelling (swelling at the site of some application of substance or injury)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Oedema peripheral (superficial swelling)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pancreatitis (inflammation of pancreas)
Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
Central nervous system stimulation
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cystitis (inflammation of the wall of the bladder)
Decreased appetite
Depression

50-59:

n/a

60+:

Depression
Hypertensive emergency
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain
Pleural effusion (water on the lungs)
Pulmonary embolism (blockage of the main artery of the lung)

What are the existing conditions these people have? *

Pain: 11 people, 22.45%
Nausea (feeling of having an urge to vomit): 5 people, 10.20%
Stress And Anxiety: 4 people, 8.16%
Therapeutic Embolisation: 3 people, 6.12%
Premenstrual Syndrome: 3 people, 6.12%
Depression: 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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