Zarxio and Valacyclovir hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zarxio (filgrastim-sndz) and Valacyclovir hydrochloride (valacyclovir hydrochloride). Common drug interactions include drug ineffective among females and agranulocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Zarxio and Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Zarxio?

Zarxio has active ingredients of filgrastim-sndz. eHealthMe is studying from 3,250 Zarxio users. Check the latest studies of Zarxio.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.



On Jul, 07, 2026

17 people who take Zarxio and Valacyclovir hydrochloride together, and have interactions are studied.

Zarxio and Valacyclovir hydrochloride drug interactions.

What are the common drug interactions of Zarxio and Valacyclovir Hydrochloride, by gender? *:

female:

  1. Drug ineffective
  2. Memory impairment
  3. Muscular weakness (muscle weakness)
  4. Neuralgia (pain in one or more nerves)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Peripheral swelling
  7. Post lumbar puncture syndrome
  8. Pruritus (severe itching of the skin)
  9. Rash
  10. Cellulitis (infection under the skin)

male:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Anaemia (lack of blood)
  3. Haemoglobin decreased
  4. Hypokalaemia (low potassium)
  5. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  6. Infection
  7. Lymphocyte count decreased
  8. Lymphocyte percentage decreased
  9. Monoclonal immunoglobulin present
  10. Monocyte percentage increased

What are the common drug interactions of Zarxio and Valacyclovir Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Drug ineffective
  2. Memory impairment
  3. Muscular weakness (muscle weakness)
  4. Neuralgia (pain in one or more nerves)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Peripheral swelling
  7. Post lumbar puncture syndrome
  8. Pruritus (severe itching of the skin)
  9. Rash
  10. Cellulitis (infection under the skin)

60+:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Anaemia (lack of blood)
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Granulocyte count increased
  5. Haematocrit decreased
  6. Haemoglobin decreased
  7. Hypokalaemia (low potassium)
  8. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  9. Infection
  10. Lymphocyte count decreased

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 9 people, 52.94%
  2. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 17.65%
  3. Neoplasm Malignant (cancer tumour): 1 person, 5.88%
  4. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.88%
  5. Acute Lymphocytic Leukaemia (In Remission): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Zarxio and Valacyclovir hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zarxio and Valacyclovir hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zarxio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valacyclovir hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zarxio and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valacyclovir hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim-sndz and valacyclovir hydrochloride (the active ingredients of Zarxio and Valacyclovir hydrochloride, respectively), and Zarxio and Valacyclovir hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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