Zetia and Azopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zetia (ezetimibe) and Azopt (brinzolamide). Common drug interactions include pancreatitis acute among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Zetia and Azopt. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

What is Azopt?

Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.

On Jul, 08, 2026

59 people who take Zetia and Azopt together, and have interactions are studied.

What are the common drug interactions of Zetia and Azopt, by gender? *:

female:

Pancreatitis acute (sudden inflammation of pancreas)
Platelet count increased
Precancerous skin lesion
Pruritus (severe itching of the skin)
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Respiratory disorder (respiratory disease)
Retinal vein occlusion (a blockage of the small veins that carry blood away from the retina)
Salmonella test positive

male:

Headache (pain in head)
Drug ineffective
Anaemia (lack of blood)
Atelectasis (partial or complete collapse of the lung)
Blindness
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Eye disorder

What are the common drug interactions of Zetia and Azopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaemia (lack of blood)
Dizziness
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haemorrhage (bleeding)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Tremor (trembling or shaking movements in one or more parts of your body)

20-29:

Clostridium test positive
Conjunctivitis bacterial (infection of conjunctiva by bacteria)
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Enterocolitis bacterial
Gastritis (inflammation of stomach)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Lupus enteritis (a chronic inflammatory autoimmune disorder that may affect intestines)
Nausea (feeling of having an urge to vomit)
Pancreatitis acute (sudden inflammation of pancreas)

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Diarrhoea
Optic nerve disorder (disease of optic nerve)

60+:

Dyspnoea (difficult or laboured respiration)
Drug ineffective
Hip fracture
Pituitary-dependent cushing's syndrome (pituitary dependent hypercortisolism)
Renovascular hypertension (a syndrome which consists of high blood pressure caused by the kidneys hormonal response)
Upper limb fracture
Wrist fracture
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Atelectasis (partial or complete collapse of the lung)
Blindness

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 11 people, 18.64%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 10 people, 16.95%
Primary Myelofibrosis (primary disorder of the bone marrow): 9 people, 15.25%
Type 2 Diabetes: 4 people, 6.78%
High Blood Pressure: 4 people, 6.78%
Depression: 4 people, 6.78%
Pain: 4 people, 6.78%
Gout (uric acid crystals building up in the body): 4 people, 6.78%
Multiple Myeloma (cancer of the plasma cells): 4 people, 6.78%
Irritable Bowel Syndrome: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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