Zetia and Nitrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zetia (ezetimibe) and Nitrol (nitroglycerin). Common drug interactions include plasma cell myeloma among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Zetia and Nitrol. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

What is Nitrol?

Nitrol has active ingredients of nitroglycerin. eHealthMe is studying from 3,069 Nitrol users. Check the latest studies of Nitrol.



On Jul, 09, 2026

57 people who take Zetia and Nitrol together, and have interactions are studied.

Zetia and Nitrol drug interactions.

What are the common drug interactions of Zetia and Nitrol, by gender? *:

female:

  1. Plasma cell myeloma (cancer that begins in plasma cells)
  2. Platelet count decreased
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  6. Urinary tract infection
  7. Abnormal dreams
  8. Acute myocardial infarction (acute heart attack)
  9. Aggression
  10. Angina pectoris (chest pain due to ischemia of the heart muscle)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Dyspepsia (indigestion)
  5. Fatigue (feeling of tiredness)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Gouty arthritis (joint inflammation with crystal formation)
  8. Influenza
  9. International normalised ratio increased
  10. Limb injury

What are the common drug interactions of Zetia and Nitrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  3. Abdominal discomfort
  4. Abdominal pain
  5. Angina pectoris (chest pain due to ischemia of the heart muscle)
  6. Anxiety
  7. Aspartate aminotransferase increased
  8. Blood creatine phosphokinase increased
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Cardiac failure congestive

40-49:

  1. Atrioventricular block (heart block)
  2. Chest pain
  3. Drug ineffective
  4. Dyspnoea (difficult or laboured respiration)
  5. Flushing (the warm, red condition of human skin)
  6. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Weight increased

50-59:

  1. Lacrimation increased
  2. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
  3. Memory impairment
  4. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  5. Myalgia (muscle pain)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Obesity (having too much body fat)
  8. Ocular hyperaemia (an abnormally large amount of blood in eye)
  9. Oropharyngeal discomfort (pain or irritation of oropharynx)
  10. Pain

60+:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Chronic kidney disease
  3. Extrasystoles
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Influenza
  6. Injection site bruising
  7. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  8. Myalgia (muscle pain)
  9. Plasma cell myeloma (cancer that begins in plasma cells)
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 19.30%
  2. Hyperlipidaemia (presence of excess lipids in the blood): 10 people, 17.54%
  3. Cardiac Disorder: 10 people, 17.54%
  4. Pain: 8 people, 14.04%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 8 people, 14.04%
  6. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 8 people, 14.04%
  7. Stable Angina (a constant chest pain): 7 people, 12.28%
  8. Depression: 7 people, 12.28%
  9. Chest Pain: 7 people, 12.28%
  10. Hypersensitivity: 6 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Zetia and Nitrol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zetia and Nitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zetia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe and nitroglycerin (the active ingredients of Zetia and Nitrol, respectively), and Zetia and Nitrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: