Ziac and Docetaxel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ziac (bisoprolol fumarate; hydrochlorothiazide) and Docetaxel (docetaxel). Common drug interactions include alopecia among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Ziac and Docetaxel. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Ziac?
Ziac has active ingredients of bisoprolol fumarate; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,451 Ziac users. Check the latest studies of Ziac.
What is Docetaxel?
Docetaxel has active ingredients of docetaxel. eHealthMe is studying from 79,875 Docetaxel users. Check the latest studies of Docetaxel.
13 people who take Ziac and Docetaxel together, and have interactions are studied.

What are the common drug interactions of Ziac and Docetaxel, by gender? *:
female:
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
- Anxiety
- Depression
- Emotional distress
- Pain
- Psychological trauma
male:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Infection
- Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
- Malaise (a feeling of general discomfort or uneasiness)
- Neutropenia (an abnormally low number of neutrophils)
- Oxygen saturation decreased
- Pleural effusion (water on the lungs)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
What are the common drug interactions of Ziac and Docetaxel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
- Anxiety
- Emotional distress
- Pain
- Psychological trauma
50-59:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Pulmonary embolism (blockage of the main artery of the lung)
- Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
- Drug toxicity
- Dyspnoea exertional (breathlessness or shortness of breath)
- Infection
- Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
60+:
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
- Anxiety
- Depression
- Blood pressure decreased
- Diarrhoea
- Malaise (a feeling of general discomfort or uneasiness)
- Neutropenia (an abnormally low number of neutrophils)
What are the existing conditions these people have? *
- Breast Cancer Female: 6 people, 46.15%
- Non-Small Cell Lung Cancer Stage Iv: 1 person, 7.69%
- Breast Cancer Metastatic: 1 person, 7.69%
- Breast Cancer: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Ziac and Docetaxel?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ziac and Docetaxel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ziac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Docetaxel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ziac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Docetaxel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Byun JS, Kang SH, Lee MJ, Kim SY, Choi HG, Lee HR, "A Case of Scleroderma-like Cutaneous Lesions Induced by Docetaxel in a Patient with Breast Cancer", Journal of Rheumatic Diseases, 2013 Oct .
- Byun JS, Kang SH, Lee MJ, Kim SY, Choi HG, Lee HR, "A Case of Scleroderma-like Cutaneous Lesions Induced by Docetaxel in a Patient with Breast Cancer", Journal of Rheumatic Diseases, 2013 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on bisoprolol fumarate; hydrochlorothiazide and docetaxel (the active ingredients of Ziac and Docetaxel, respectively), and Ziac and Docetaxel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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