Zocor and Pemetrexed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zocor (simvastatin) and Pemetrexed (pemetrexed). Common drug interactions include blood creatinine increased among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Zocor and Pemetrexed. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

What is Pemetrexed?

Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.

On Jul, 10, 2026

45 people who take Zocor and Pemetrexed together, and have interactions are studied.

What are the common drug interactions of Zocor and Pemetrexed, by gender? *:

female:

Blood creatinine increased
Hyperglycaemia (high blood sugar)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Asthenia (weakness)
Blood bicarbonate decreased
Blood chloride decreased
Blood sodium decreased
Blood urea increased
Cough
Death

male:

Pneumonia
Dehydration (dryness resulting from the removal of water)
Anxiety
Blood glucose increased
Cardiac failure congestive
Chest pain
Coronary arterial stent insertion
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Decreased appetite

What are the common drug interactions of Zocor and Pemetrexed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Pneumonia
Asthenia (weakness)
Cough
Hypophagia (reduced food intake)
Drug eruption (adverse drug reaction of the skin)
Rectal haemorrhage (bleeding from anus)
Thrombocytopenia (decrease of platelets in blood)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

60+:

Dehydration (dryness resulting from the removal of water)
Hyperglycaemia (high blood sugar)
Blood urea increased
Death
Diarrhoea
Glomerular filtration rate decreased
Hypotension (abnormally low blood pressure)
Leukocytosis (increased white blood cells)
Pain
Pco2 decreased

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 28 people, 62.22%
High Blood Pressure: 16 people, 35.56%
Constipation: 10 people, 22.22%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 20.00%
Non-Small Cell Lung Cancer Stage Iv: 7 people, 15.56%
Nausea (feeling of having an urge to vomit): 7 people, 15.56%
Stress And Anxiety: 7 people, 15.56%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 15.56%
Insomnia (sleeplessness): 6 people, 13.33%
Erection Problems: 5 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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