Zofran odt and Furosemide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zofran odt (ondansetron) and Furosemide (furosemide). Common drug interactions include gastrooesophageal reflux disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zofran odt and Furosemide. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Zofran odt?

Zofran odt has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 2,092 Zofran odt users. Check the latest studies of Zofran odt.

What is Furosemide?

Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.



On Jul, 23, 2026

55 people who take Zofran odt and Furosemide together, and have interactions are studied.

Zofran odt and Furosemide drug interactions.

What are the common drug interactions of Zofran Odt and Furosemide, by gender? *:

female:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Diarrhoea
  3. Abdominal distension
  4. Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
  5. Fall
  6. Abscess limb (limb infection)
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  9. Caudal regression syndrome (disorder that impairs the development of the lower (caudal) half of the body)
  10. Decreased activity

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Arthralgia (joint pain)
  4. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
  5. Hypotension (abnormally low blood pressure)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Renal failure acute (rapid kidney dysfunction)
  8. Tubulointerstitial nephritis and uveitis syndrome (a rare autoimmune disease a form of nephritis affecting the interstitium of the kidneys surrounding the tubules along with inflammation of the middle layer of the eye)
  9. Nephrogenic anaemia (anaemia due to kidney disease)
  10. Renal injury (kidney injury)

What are the common drug interactions of Zofran Odt and Furosemide, by age (0-1 to 60+)? *:

0-1:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Caudal regression syndrome (disorder that impairs the development of the lower (caudal) half of the body)
  3. Decreased activity
  4. Diabetic nephropathy (diabetic kidney disease)
  5. Diarrhoea
  6. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Hydronephrosis (water inside the kidney)
  9. Pericardial effusion (fluid around the heart)
  10. Post procedural complication

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Abdominal discomfort
  3. Abdominal hernia
  4. Abortion spontaneous (naturally occurring miscarriage)
  5. Alcoholism (problems with alcohol)
  6. Anaemia (lack of blood)
  7. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  8. Anxiety
  9. Arthralgia (joint pain)
  10. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)

40-49:

  1. Abdominal distension
  2. Arthralgia (joint pain)
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Neoplasm progression (growth of tumour)

50-59:

  1. Jaw fracture
  2. Joint dislocation (a joint position is changed from normal position)
  3. Leukopenia (less number of white blood cells in blood)
  4. Long qt syndrome (disorder of the heart's electrical system)
  5. Loss of consciousness
  6. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  7. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  8. Mitral valve prolapse (heart's mitral valve doesn't work well)
  9. Multiple fractures
  10. Multiple pregnancy (pregnancy where more than one foetus develops simultaneously in the womb)

60+:

  1. Chronic kidney disease
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Gout (uric acid crystals building up in the body)
  4. Cardiac valve disease (heart valve disease)
  5. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  6. Embolic stroke (stroke due to obstruction due to an embolus)
  7. Fall
  8. Fatigue (feeling of tiredness)
  9. Neuropathy peripheral (surface nerve damage)
  10. Plasma cell myeloma (cancer that begins in plasma cells)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 18.18%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 14.55%
  3. Pain: 6 people, 10.91%
  4. High Blood Pressure: 5 people, 9.09%
  5. Primary Immunodeficiency Syndrome: 4 people, 7.27%
  6. High Blood Cholesterol: 4 people, 7.27%
  7. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 7.27%
  8. Anaemia (lack of blood): 4 people, 7.27%
  9. Renal Disorder (kidney disease): 3 people, 5.45%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zofran odt and Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zofran odt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zofran odt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Furosemide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ondansetron and furosemide (the active ingredients of Zofran odt and Furosemide, respectively), and Zofran odt and Furosemide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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