Zoledronic and Vepesid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoledronic (zoledronic acid) and Vepesid (etoposide). Common drug interactions include sepsis among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Zoledronic and Vepesid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Vepesid?

Vepesid has active ingredients of etoposide. eHealthMe is studying from 2,267 Vepesid users. Check the latest studies of Vepesid.

On Jul, 11, 2026

14 people who take Zoledronic and Vepesid together, and have interactions are studied.

Zoledronic and Vepesid drug interactions.

What are the common drug interactions of Zoledronic and Vepesid, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
Klebsiella infection
Febrile neutropenia (fever with reduced white blood cells)
Renal failure acute (rapid kidney dysfunction)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anaemia (lack of blood)

male:

Febrile neutropenia (fever with reduced white blood cells)
White blood cell disorder
Small cell lung cancer metastatic (lung cancer spreads to other body parts)
Back pain
Blood creatine phosphokinase increased
Bone marrow failure
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer)
Erythema (redness of the skin)
Face oedema (swelling of face)
Metastases to bone (cancer spreads to bone)

What are the common drug interactions of Zoledronic and Vepesid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Klebsiella infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Bacterial infection
Chills (felling of cold)
Hyperthermia (body temperature greatly above normal)

20-29:

Renal tubular disorder (disease of kidney tubules)

30-39:

Anaemia (lack of blood)
Anorectal disorder
Chest pain
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypermetropia (abnormal condition in which vision for distant objects is better than for near objects)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

40-49:

Febrile neutropenia (fever with reduced white blood cells)

50-59:

n/a

60+:

Febrile neutropenia (fever with reduced white blood cells)
White blood cell disorder
Erythema (redness of the skin)
Face oedema (swelling of face)
Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
Metastases to bone (cancer spreads to bone)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Myelofibrosis (a disease in which abnormal blood cells and fibres build up inside the bone marrow)
Neoplasm malignant (cancer tumour)
Small cell lung cancer metastatic (lung cancer spreads to other body parts)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 35.71%
Bone Sarcoma (bone cancer): 5 people, 35.71%
Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 21.43%
Small Cell Lung Cancer Stage Unspecified (lung cancer in unknown stage): 1 person, 7.14%
Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
Metastases To Spine (cancer spreads to spine): 1 person, 7.14%
Insomnia (sleeplessness): 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Cancer Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and Vepesid?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously