Zoloft and Anzemet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Anzemet (dolasetron mesylate). Common drug interactions include fatigue among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Anzemet. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Anzemet?

Anzemet has active ingredients of dolasetron mesylate. eHealthMe is studying from 2,603 Anzemet users. Check the latest studies of Anzemet.

On Jul, 16, 2026

99 people who take Zoloft and Anzemet together, and have interactions are studied.

What are the common drug interactions of Zoloft and Anzemet, by gender? *:

female:

Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Vomiting
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Lung neoplasm (tumour of lung)
Bone disorder
Pain
Pneumonia
Anaemia (lack of blood)

male:

Pleural effusion (water on the lungs)
Hypertension (high blood pressure)
Haematuria (presence of blood in urine)
Renal failure (kidney dysfunction)
Cardiac arrest
Osteonecrosis of jaw (death of bone of jaw)
Atelectasis (partial or complete collapse of the lung)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cataract (clouding of the lens inside the eye)

What are the common drug interactions of Zoloft and Anzemet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia of chronic disease
Anaphylactic reaction (serious allergic reaction)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angioedema (rapid swelling of the dermis)
Arrhythmia (irregular heartbeat)
Arteritis (inflammation of the walls of arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy

30-39:

Nasal passage irritation
Sneezing

40-49:

Abdominal hernia
Back pain
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Compression fracture (fracture due to pressure caused by injury)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
General physical health deterioration (weak health status)
Injury
Iron deficiency anaemia
Joint injury
Metastases to spine (cancer spreads to spine)

50-59:

Diarrhoea
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Arthralgia (joint pain)
General physical health deterioration (weak health status)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Abdominal hernia
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Compression fracture (fracture due to pressure caused by injury)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

60+:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Abdominal pain
Back pain
Oedema peripheral (superficial swelling)
Vomiting
Contusion (a type of hematoma of tissue in which capillaries)
Headache (pain in head)
Osteonecrosis of jaw (death of bone of jaw)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 24 people, 24.24%
Stress And Anxiety: 18 people, 18.18%
Multiple Myeloma (cancer of the plasma cells): 15 people, 15.15%
Pain In Jaw: 14 people, 14.14%
Pain: 12 people, 12.12%
Breast Cancer: 7 people, 7.07%
High Blood Pressure: 6 people, 6.06%
Anaemia (lack of blood): 6 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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