Zonisamide and Ezetimibe drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zonisamide (zonisamide) and Ezetimibe (ezetimibe). Common drug interactions include pain among females and tubulointerstitial nephritis among males.

The phase IV clinical study analyzes what interactions people have when they take Zonisamide and Ezetimibe. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.

On Jul, 20, 2026

28 people who take Zonisamide and Ezetimibe together, and have interactions are studied.

Zonisamide and Ezetimibe drug interactions.

What are the common drug interactions of Zonisamide and Ezetimibe, by gender? *:

female:

Pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Alopecia (absence of hair from areas of the body)
Drug ineffective
Infection
Pyrexia (fever)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Haematuria (presence of blood in urine)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

male:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Pain
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain in extremity
Renal failure (kidney dysfunction)
Rib fracture
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Fibula fracture

What are the common drug interactions of Zonisamide and Ezetimibe, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Abdominal distension
Abdominal pain
Blood glucose increased
Constipation
Cough
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Impaired gastric emptying
Nausea (feeling of having an urge to vomit)

40-49:

n/a

50-59:

Drug ineffective
Fatigue (feeling of tiredness)
Infection
Hypotension (abnormally low blood pressure)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Haematuria (presence of blood in urine)
Headache (pain in head)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperhidrosis (abnormally increased sweating)
Ill-defined disorder

60+:

Headache (pain in head)
Joint range of motion decreased (disease of joint movement)
Limb injury
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pain
Pain in extremity
Pyrexia (fever)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 6 people, 21.43%
Itching: 5 people, 17.86%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 14.29%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 14.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 14.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 10.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.14%
Immunodeficiency: 2 people, 7.14%
Hiv Infection: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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