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Zyprexa and Kyprolis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyprexa (olanzapine) and Kyprolis (carfilzomib). Common drug interactions include vomiting among females and febrile infection among males.

The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Kyprolis. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

What is Kyprolis?

Kyprolis has active ingredients of carfilzomib. It is often used in multiple myeloma. eHealthMe is studying from 15,080 Kyprolis users. Check the latest studies of Kyprolis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

19 people who take Zyprexa and Kyprolis together, and have interactions are studied.

Zyprexa and Kyprolis drug interactions.

What are the common drug interactions of Zyprexa and Kyprolis, by gender? *:

female:

  1. Vomiting
  2. Decreased appetite
  3. Flatulence (flatus expelled through the anus)
  4. Nausea (feeling of having an urge to vomit)
  5. Nodule (a growth of abnormal tissue)

male:

  1. Febrile infection (infection with temperature rise)
  2. Neuropathy peripheral (surface nerve damage)
  3. Pain
  4. Pyrexia (fever)
  5. Renal impairment (severely reduced kidney function)
  6. Skin discolouration (change of skin colour)

What are the common drug interactions of Zyprexa and Kyprolis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Decreased appetite
  2. Febrile infection (infection with temperature rise)
  3. Nausea (feeling of having an urge to vomit)
  4. Pyrexia (fever)
  5. Renal impairment (severely reduced kidney function)
  6. Vomiting

60+:

n/a

What are the existing conditions these people have? *

  1. Stress And Anxiety: 1 person, 5.26%
  2. Pain: 1 person, 5.26%
  3. Neuralgia (pain in one or more nerves): 1 person, 5.26%
  4. Nausea (feeling of having an urge to vomit): 1 person, 5.26%
  5. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Zyprexa and Kyprolis?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zyprexa and Kyprolis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kyprolis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyprexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kyprolis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on olanzapine and carfilzomib (the active ingredients of Zyprexa and Kyprolis, respectively), and Zyprexa and Kyprolis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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