Zyrtec and Inflectra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Inflectra (infliximab-dyyb). Common drug interactions include colitis ulcerative among females and peripheral swelling among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Inflectra. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,620 Zyrtec users. Check the latest studies of Zyrtec.

What is Inflectra?

Inflectra has active ingredients of infliximab-dyyb. eHealthMe is studying from 52,370 Inflectra users. Check the latest studies of Inflectra.

On Aug, 09, 2026

25 people who take Zyrtec and Inflectra together, and have interactions are studied.

What are the common drug interactions of Zyrtec and Inflectra, by gender? *:

female:

Colitis ulcerative (inflammation of colon with ulcer)
Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
Anxiety
Cough
Drug hypersensitivity
Dysphonia (speech disorder attributable to a disorder of phonation)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Infusion related reaction
Oropharyngeal pain
Psoriasis (immune-mediated disease that affects the skin)

male:

Peripheral swelling
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Skin discolouration (change of skin colour)
Skin mass
Therapeutic response decreased (less preventive response)
Diarrhoea
Epistaxis (bleed from the nose)
Erythema of eyelid (redness of the eyelid)
Eye irritation
Hepatic enzyme increased

What are the common drug interactions of Zyrtec and Inflectra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Peripheral swelling
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Diarrhoea
Erythema of eyelid (redness of the eyelid)
Eye irritation
Hepatic enzyme increased
Hyperhidrosis (abnormally increased sweating)
Infection
Pyrexia (fever)
Skin discolouration (change of skin colour)

20-29:

n/a

30-39:

Psoriasis (immune-mediated disease that affects the skin)
Stress
Therapeutic response unexpected
Anxiety

40-49:

Cough
Dysphonia (speech disorder attributable to a disorder of phonation)
Oropharyngeal pain

50-59:

Drug hypersensitivity
Infusion related reaction

60+:

Colitis ulcerative (inflammation of colon with ulcer)
Pruritus (severe itching of the skin)
Drug hypersensitivity
Hypersensitivity

What are the existing conditions these people have? *

Pyoderma Gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance): 4 people, 16.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 12.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 12.00%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 8.00%
Asthma: 2 people, 8.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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