Zyrtec and Transderm scop drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Transderm scop (scopolamine). Common drug interactions include myalgia among females and therapeutic response unexpected among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Transderm scop. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

What is Transderm scop?

Transderm scop has active ingredients of scopolamine. It is often used in motion sickness. eHealthMe is studying from 3,011 Transderm scop users. Check the latest studies of Transderm scop.



On Jul, 07, 2026

72 people who take Zyrtec and Transderm scop together, and have interactions are studied.

Zyrtec and Transderm scop drug interactions.

What are the common drug interactions of Zyrtec and Transderm Scop, by gender? *:

female:

  1. Myalgia (muscle pain)
  2. Pruritus (severe itching of the skin)
  3. Therapeutic response unexpected
  4. Abdominal discomfort
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cerebrospinal fluid leakage
  7. Confusional state
  8. Death
  9. Drug hypersensitivity
  10. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

male:

  1. Therapeutic response unexpected
  2. Ascites (accumulation of fluid in the abdominal cavity)
  3. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  4. Hepatic failure (liver failure)
  5. Hypotension (abnormally low blood pressure)
  6. Ileus (a painful obstruction of the ileum or other part of the intestine)
  7. Klebsiella infection
  8. Livedo reticularis (a lace-like purplish discoloration of the skin)
  9. Pancreatitis (inflammation of pancreas)
  10. Pleural effusion (water on the lungs)

What are the common drug interactions of Zyrtec and Transderm Scop, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cough
  2. Dry eye (lack of adequate tears)
  3. Head discomfort
  4. Sinusitis (inflammation of sinus)
  5. Drug hypersensitivity
  6. Abdominal discomfort
  7. Application site burn
  8. Application site discolouration
  9. Application site erythema (redness of the skin at application site)
  10. Application site exfoliation (application site removal of the oldest dead skin cells on the skin's outermost surface)

30-39:

  1. Anxiety
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Arrhythmia (irregular heartbeat)
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Emotional distress
  7. Headache (pain in head)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  10. Muscle spasms (muscle contraction)

40-49:

  1. Anxiety
  2. Arrhythmia (irregular heartbeat)
  3. Cardiac flutter (abnormal heart rhythm)
  4. Crying
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  7. Dry mouth
  8. Feeling drunk
  9. Irritability
  10. Lethargy (tiredness)

50-59:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Malignant melanoma (skin cancer rises from melancytes)
  3. Memory impairment
  4. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  5. Mobility decreased (ability to move is reduced)
  6. Mood swings (an extreme or rapid change in mood)
  7. Muscle spasms (muscle contraction)
  8. Muscular weakness (muscle weakness)
  9. Myalgia (muscle pain)
  10. Myositis (inflammation of the muscles)

60+:

  1. Erythema (redness of the skin)
  2. Haemorrhage intracranial (bleeding within the skull)
  3. Faeces discoloured
  4. Hallucination (an experience involving the perception of something not present)
  5. Headache (pain in head)
  6. Impaired reasoning
  7. Initial insomnia (feeling of inadequate or poor-quality sleep)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Memory impairment
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 31 people, 43.06%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 18 people, 25.00%
  3. Pain: 14 people, 19.44%
  4. Nausea (feeling of having an urge to vomit): 8 people, 11.11%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 9.72%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 9.72%
  7. Hypersensitivity: 6 people, 8.33%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.33%
  9. Depression: 5 people, 6.94%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 6.94%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zyrtec and Transderm scop:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Transderm scop:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyrtec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Transderm scop and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cetirizine hydrochloride and scopolamine (the active ingredients of Zyrtec and Transderm scop, respectively), and Zyrtec and Transderm scop (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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