Zyrtec and Viramune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyrtec (cetirizine hydrochloride) and Viramune (nevirapine). Common drug interactions include anhedonia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Zyrtec and Viramune. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,620 Zyrtec users. Check the latest studies of Zyrtec.

What is Viramune?

Viramune has active ingredients of nevirapine. It is often used in hiv infection. eHealthMe is studying from 11,381 Viramune users. Check the latest studies of Viramune.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

61 people who take Zyrtec and Viramune together, and have interactions are studied.

What are the common drug interactions of Zyrtec and Viramune, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Headache (pain in head)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Liver transplant
Osteoporosis (bones weak and more likely to break)

male:

Anxiety
Emotional distress
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pancreatitis (inflammation of pancreas)
Pleural effusion (water on the lungs)
Bone density decreased
Bradycardia (abnormally slow heart action)

What are the common drug interactions of Zyrtec and Viramune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Depression
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Headache (pain in head)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Lipohypertrophy (a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin)
Pharyngotonsillitis (inflammation of the pharynx and the tonsils)
Sinusitis (inflammation of sinus)
Suicide attempt
Hidradenitis (chronic disease of a type of sweat gland)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)

30-39:

Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Hypoaesthesia (reduced sense of touch or sensation)
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Myalgia (muscle pain)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Bone density decreased
Burns

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Osteoporosis (bones weak and more likely to break)
Pain
Bone density decreased
Abdominal pain
Chest pain
Chronic kidney disease
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Dry throat
Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Bipolar disorder (mood disorder)
Cardiac arrest
Chronic kidney disease

60+:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Fatigue (feeling of tiredness)
Blood bilirubin increased
Blood creatinine increased
Depression
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Hypoaesthesia (reduced sense of touch or sensation)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Osteopenia (a condition where bone mineral density is lower than normal)
Alanine aminotransferase increased

What are the existing conditions these people have? *

Hypersensitivity: 6 people, 9.84%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.20%
High Blood Cholesterol: 4 people, 6.56%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 6.56%
Chest Pain: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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