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A study for a 58 year old woman who takes Trazodone Hydrochloride (an AI-powered real world drug study)

Summary:

18,717 females aged 58 (±5) who take the same drug and have adverse effects are studied. This is a phase IV clinical study for a 58 year old female patient who has Major Depression. The study is created by eHealthMe based on reports from sources including the FDA.


On Jun, 17, 2026

18,717 females aged 58 (±5) who take Trazodone Hydrochloride and have adverse effects are studied.


Number of reports submitted per year:

Trazodone Hydrochloride for a 58-year old woman.

Information of the patient in this study:

  • Age: 58
  • Gender: female

What are the drugs?

What are the conditions?

  • Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings) is found to be associated with 805 drugs and 1,474 conditions by eHealthMe. Check the latest studies of Major depression.

What are the adverse effects?


Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

  • Iron Deficiency:
    - among females aged 58 (±5) who take the same drug: 0% (0 of 18,717)
    - among people who take the same drug, regardless of gender or age: 0% (4 of 140,860)

By each condition:

  • people who have Iron Deficiency with Major Depression:
    - among females aged 58 (±5) who have Major Depression: 0% (0 of 3,163)
    - among people who have Major Depression, regardless of gender or age: 0.01% (3 of 31,832)

By each drug (FDA data only):

  • people who take Trazodone Hydrochloride and have Iron Deficiency:
    - among females aged 58 (±5) who take Trazodone Hydrochloride and have side effects: 0% (0 of 2,040)
    - among people who take Trazodone Hydrochloride and have side effects, regardless of gender or age: 0.02% (4 of 17,399)

Common side effects *:

  1. Headache (pain in head): 1,997 people, 10.67%
  2. Fatigue (feeling of tiredness): 1,686 people, 9.01%
  3. Nausea (feeling of having an urge to vomit): 1,684 people, 9.00%
  4. Drug Ineffective : 1,496 people, 7.99%
  5. Pain : 1,473 people, 7.87%
  6. Dyspnea (difficult or laboured breathing): 1,451 people, 7.75%
  7. Diarrhea : 1,282 people, 6.85%
  8. High Blood Pressure : 1,252 people, 6.69%
  9. Stress And Anxiety : 1,107 people, 5.91%
  10. Joint Pain : 1,067 people, 5.70%
  11. Dizziness : 1,056 people, 5.64%
  12. Fall : 1,034 people, 5.52%
  13. Weakness : 943 people, 5.04%
  14. Nausea And Vomiting : 875 people, 4.67%
  15. Malaise (a feeling of general discomfort or uneasiness): 816 people, 4.36%
  16. Rashes (redness): 799 people, 4.27%
  17. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 778 people, 4.16%
  18. Weight Decreased : 759 people, 4.06%
  19. Pain In Extremity : 753 people, 4.02%
  20. Pneumonia : 736 people, 3.93%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

  1. Pain : 1,849 people, 9.88%
  2. Stress And Anxiety : 1,703 people, 9.10%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1,701 people, 9.09%
  4. High Blood Pressure : 1,551 people, 8.29%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1,350 people, 7.21%
  6. High Blood Cholesterol : 1,172 people, 6.26%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1,083 people, 5.79%
  8. Asthma : 815 people, 4.35%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 675 people, 3.61%
  10. Migraine (headache): 622 people, 3.32%
  11. Diabetes : 561 people, 3.00%
  12. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 546 people, 2.92%
  13. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 520 people, 2.78%
  14. Bipolar Disorder (mood disorder): 517 people, 2.76%
  15. Nausea (feeling of having an urge to vomit): 516 people, 2.76%
  16. Hypersensitivity : 450 people, 2.40%
  17. Muscle Spasms (muscle contraction): 404 people, 2.16%
  18. Psoriasis (immune-mediated disease that affects the skin): 399 people, 2.13%
  19. Osteoporosis (bones weak and more likely to break): 387 people, 2.07%
  20. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 382 people, 2.04%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

  1. Cymbalta (1,624 people, 8.68%)
  2. Lyrica (1,515 people, 8.09%)
  3. Synthroid (1,461 people, 7.81%)
  4. Prednisone (1,181 people, 6.31%)
  5. Nexium (1,140 people, 6.09%)
  6. Vitamin D3 (1,137 people, 6.07%)
  7. Pantoprazole (1,116 people, 5.96%)
  8. Humira (1,107 people, 5.91%)
  9. Metformin (1,084 people, 5.79%)
  10. Xanax (1,073 people, 5.73%)
  11. Vitamin D (1,071 people, 5.72%)
  12. Clonazepam (1,034 people, 5.52%)
  13. Gabapentin (991 people, 5.29%)
  14. Prilosec (966 people, 5.16%)
  15. Tylenol (919 people, 4.91%)
  16. Lipitor (892 people, 4.77%)
  17. Vitamin B12 (888 people, 4.74%)
  18. Amlodipine (869 people, 4.64%)
  19. Zoloft (857 people, 4.58%)
  20. Singulair (836 people, 4.47%)

Drug effectiveness *:

Trazodone Hydrochloride:
  • not at all: 2.85 %
  • somewhat: 15.26 %
  • moderate: 29.67 %
  • high: 37.66 %
  • very high: 14.55 %

* Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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Symptoms:

Drugs that are associated with:

Conditions that are associated with:

How the phase IV clinical study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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