Cladribine side effects - from FDA reports


In this review, we analyze Cladribine side effects by the time on the drug, gender and age of the people who have side effects while taking Cladribine. The review is based on 1,223 people who have side effects while taking the drug from FDA, and is updated regularly.

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Cladribine

Cladribine has active ingredients of cladribine. (latest outcomes from Cladribine 1,226 users)


On Dec, 01, 2018

1,223 people who take Cladribine are studied.


Number of reports submitted per year:

Cladribine side effects.

Most common side effects over time *:

< 1 month:
  • Febrile neutropenia (fever with reduced white blood cells)
  • Cystitis haemorrhagic (blood in the urine and painful voiding)
  • Drug eruption (adverse drug reaction of the skin)
  • Pneumonia
  • Sepsis (a severe blood infection that can lead to organ failure and death)
1 - 6 months:
  • Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  • Second primary malignancy (after getting cure a cancer, a new cancer development)
  • Weight decreased
  • Osteoporosis (bones weak and more likely to break)
  • Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
6 - 12 months:
  • Lung neoplasm malignant (cancer tumour of lung)
  • Maternal exposure during pregnancy (use of substance during pregnancy)
  • Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  • Pregnancy
  • Richter's syndrome (hairy cell cancer changes in fast growing b cell cancer tumour)
1 - 2 years:
  • Oesophageal carcinoma (cancer tumour of oesophagus)
  • Throat cancer
  • Thrombocytopenia (decrease of platelets in blood)
2 - 5 years:
  • Pyrexia (fever)
5 - 10 years:

n/a

10+ years:
  • Pyrexia (fever)
not specified:
  • Thrombocytopenia (decrease of platelets in blood)
  • Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  • Pyrexia (fever)
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Anaemia haemolytic autoimmune (condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)

Click here to view more results or personalize the results to your gender and age

Most common side effects by gender *:

female:
  • Thrombocytopenia (decrease of platelets in blood)
  • Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  • Pneumonia
  • Pyrexia (fever)
  • Vomiting
male:
  • Thrombocytopenia (decrease of platelets in blood)
  • Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  • Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  • Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  • Upper respiratory tract infection

Click here to view more results or personalize the results to your gender and age

Most common side effects by age *:

0-1:
  • Langerhans' cell histiocytosis
  • Venoocclusive disease (small veins in the liver are obstructed)
  • Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  • Febrile neutropenia (fever with reduced white blood cells)
  • Primitive neuroectodermal tumour (neural crest tumour)
2-9:
  • Drug ineffective
  • Pyrexia (fever)
  • Streptococcal sepsis (whole body inflammation by streptococcal)
  • Febrile neutropenia (fever with reduced white blood cells)
  • Respiratory distress (difficulty in breathing)
10-19:
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Thrombocytopenia (decrease of platelets in blood)
  • Pyrexia (fever)
  • Venoocclusive liver disease (small veins in the liver are obstructed)
  • Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
20-29:
  • Diarrhoea
  • Epistaxis (bleed from the nose)
  • Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
  • Malignant neoplasm progression (cancer tumour came back)
  • Neutropenia (an abnormally low number of neutrophils)
30-39:
  • Thrombocytopenia (decrease of platelets in blood)
  • Febrile neutropenia (fever with reduced white blood cells)
  • Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  • Pyrexia (fever)
  • Thyroiditis (inflammation of thyroid gland)
40-49:
  • Thrombocytopenia (decrease of platelets in blood)
  • Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  • Neutropenia (an abnormally low number of neutrophils)
  • Upper respiratory tract infection
  • Pneumonia
50-59:
  • Pneumonia
  • Oesophageal carcinoma (cancer tumour of oesophagus)
  • Thrombocytopenia (decrease of platelets in blood)
  • Malignant neoplasm progression (cancer tumour came back)
  • Nervous system disorder (a general class of medical conditions affecting the nervous system)
60+:
  • Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  • Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  • Thrombocytopenia (decrease of platelets in blood)
  • Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  • Pyrexia (fever)

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

You are not alone:

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On eHealthMe, Cladribine (cladribine) is often used to treat hairy cell leukaemia. Find out below the conditions the drugs are used for and how effective they are.


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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