Abilify and Motormental retardation - a phase IV clinical study of FDA data

Summary:

Motormental retardation is reported as a side effect among people who take Abilify (aripiprazole), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Sertraline, and have Schizotypal personality disorder.

The phase IV clinical study analyzes which people have Motormental retardation when taking Abilify. It is created by eHealthMe based on reports of 97,308 people who have side effects when taking Abilify from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

What is Motormental retardation?

Motormental retardation (a slowing-down of thought and a reduction of physical work) is found to be associated with 271 drugs and 748 conditions by eHealthMe. Check the latest studies of Motormental retardation.



On May, 01, 2026

97,308 people reported to have side effects when taking Abilify.
Among them, 69 people (0.07%) have Motormental retardation.

Could Abilify cause Motormental retardation?

Among these 69 people:

How long have people been on Abilify when they have Motormental retardation? *

  • < 1 month: 61.11 %
  • 1 - 6 months: 22.22 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 5.56 %
  • 2 - 5 years: 11.11 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Motormental retardation when taking Abilify? *

  • female: 32.84 %
  • male: 67.16 %

What is the age of people who have Motormental retardation when taking Abilify? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.29 %
  • 20-29: 4.84 %
  • 30-39: 27.42 %
  • 40-49: 16.13 %
  • 50-59: 25.81 %
  • 60+: 14.52 %

What are other drugs people take besides Abilify? *

  1. Sertraline: 15 people, 21.74%
  2. Risperdal: 5 people, 7.25%
  3. Clonazepam: 4 people, 5.80%
  4. Zyprexa: 3 people, 4.35%
  5. Trileptal: 3 people, 4.35%
  6. Depakote: 3 people, 4.35%
  7. Effexor: 3 people, 4.35%
  8. Lamictal: 3 people, 4.35%
  9. Valproate Sodium: 3 people, 4.35%
  10. Amlodipine: 2 people, 2.90%

What are other side effects people have besides Motormental retardation? *

  1. Overdose: 21 people, 30.43%
  2. Nausea And Vomiting: 17 people, 24.64%
  3. Nausea (feeling of having an urge to vomit): 16 people, 23.19%
  4. Fever: 12 people, 17.39%
  5. Blood Creatine Phosphokinase Increased: 10 people, 14.49%
  6. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 9 people, 13.04%
  7. Salivary Hypersecretion (excess saliva secretion): 8 people, 11.59%
  8. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 8 people, 11.59%
  9. Catatonia (unresponsive to external stimuli): 8 people, 11.59%
  10. Delirium (wild excitement): 8 people, 11.59%

What are the existing conditions these people have? *

  1. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 16 people, 23.19%
  2. Schizotypal Personality Disorder (a personality disorder characterized by a need for social isolation, anxiety in social situations): 16 people, 23.19%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 11 people, 15.94%
  4. Delusion (a false belief or opinion): 7 people, 10.14%
  5. Affective Disorder (mental disorder): 4 people, 5.80%
  6. Psychotic Disorder: 3 people, 4.35%
  7. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 4.35%
  8. Insomnia (sleeplessness): 3 people, 4.35%
  9. Depressed Mood: 3 people, 4.35%
  10. Pain: 2 people, 2.90%

* Approximation only. Some reports may have incomplete information.

Do you take Abilify and have Motormental retardation?

- Check whether Motormental retardation is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Abilify:

Motormental retardation treatments and more:

How severe was Motormental retardation and when was it recovered:

Expand to all the drugs that have ingredients of aripiprazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Motormental retardation:

Browse all the conditions that are associated with Motormental retardation:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole (the active ingredients of Abilify) and Abilify (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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