Abilify and Pyrosis - a phase IV clinical study of FDA data

Summary:

Pyrosis is reported as a side effect among people who take Abilify (aripiprazole), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Cymbalta, and have Pain.

The phase IV clinical study analyzes which people have Pyrosis when taking Abilify. It is created by eHealthMe based on reports of 97,308 people who have side effects when taking Abilify from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,441 Abilify users. Check the latest studies of Abilify.

What is Pyrosis?

Pyrosis (painful burning sensation in the chest caused by gastroesophageal reflux) is found to be associated with 3,609 drugs and 3,455 conditions by eHealthMe. Check the latest studies of Pyrosis.



On Aug, 20, 2025

97,308 people reported to have side effects when taking Abilify.
Among them, 603 people (0.62%) have Pyrosis.

Could Abilify cause Pyrosis?

Among these 603 people:

How long have people been on Abilify when they have Pyrosis? *

  • < 1 month: 13.51 %
  • 1 - 6 months: 33.78 %
  • 6 - 12 months: 4.05 %
  • 1 - 2 years: 12.16 %
  • 2 - 5 years: 21.62 %
  • 5 - 10 years: 9.46 %
  • 10+ years: 5.41 %

What is the gender of people who have Pyrosis when taking Abilify? *

  • female: 75.04 %
  • male: 24.96 %

What is the age of people who have Pyrosis when taking Abilify? *

  • 0-1: 1.15 %
  • 2-9: 0.46 %
  • 10-19: 2.53 %
  • 20-29: 8.76 %
  • 30-39: 11.06 %
  • 40-49: 19.59 %
  • 50-59: 43.55 %
  • 60+: 12.9 %

What are other drugs people take besides Abilify? *

  1. Cymbalta: 153 people, 25.37%
  2. Seroquel: 135 people, 22.39%
  3. Wellbutrin: 133 people, 22.06%
  4. Tylenol: 120 people, 19.90%
  5. Lyrica: 114 people, 18.91%
  6. Morphine: 106 people, 17.58%
  7. Topamax: 106 people, 17.58%
  8. Fluoxetine: 101 people, 16.75%
  9. Prilosec: 100 people, 16.58%
  10. Lexapro: 99 people, 16.42%

What are other side effects people have besides Pyrosis? *

  1. Stress And Anxiety: 235 people, 38.97%
  2. Nausea (feeling of having an urge to vomit): 193 people, 32.01%
  3. Dizziness: 176 people, 29.19%
  4. Headache (pain in head): 163 people, 27.03%
  5. Diarrhea: 152 people, 25.21%
  6. Indigestion: 149 people, 24.71%
  7. Migraine (headache): 148 people, 24.54%
  8. Weight Increased: 146 people, 24.21%
  9. Weight Decreased: 141 people, 23.38%
  10. Memory Loss: 136 people, 22.55%

What are the existing conditions these people have? *

  1. Pain: 100 people, 16.58%
  2. Migraine (headache): 96 people, 15.92%
  3. Stress And Anxiety: 84 people, 13.93%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 49 people, 8.13%
  5. High Blood Pressure: 43 people, 7.13%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 43 people, 7.13%
  7. High Blood Cholesterol: 41 people, 6.80%
  8. Sleep Disorder: 31 people, 5.14%
  9. Insomnia (sleeplessness): 29 people, 4.81%
  10. Irritable Bowel Syndrome: 25 people, 4.15%

* Approximation only. Some reports may have incomplete information.

Do you take Abilify and have Pyrosis?

- Check whether Pyrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Abilify:

Pyrosis treatments and more:

How severe was Pyrosis and when was it recovered:

Expand to all the drugs that have ingredients of aripiprazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Abilify side effects:

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Pyrosis:

Browse all the drugs that are associated with Pyrosis:

Common conditions associated with Pyrosis:

Browse all the conditions that are associated with Pyrosis:

Drugs similar to Abilify and Pyrosis :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole (the active ingredients of Abilify) and Abilify (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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