Acetaminophen and codeine phosphate and Peptic ulcer aggravated - a phase IV clinical study of FDA data

Summary:

Peptic ulcer aggravated is reported as a side effect among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate), especially for people who are female, 60+ old, also take Naproxen, and have High blood pressure.

The phase IV clinical study analyzes which people have Peptic ulcer aggravated when taking Acetaminophen and codeine phosphate. It is created by eHealthMe based on reports of 2,908 people who have side effects when taking Acetaminophen and codeine phosphate from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Peptic ulcer aggravated?

Peptic ulcer aggravated is found to be associated with 1,488 drugs and 545 conditions by eHealthMe. Check the latest studies of Peptic ulcer aggravated.

On Jul, 10, 2026

2,908 people reported to have side effects when taking Acetaminophen and codeine phosphate.
Among them, 51 people (1.75%) have Peptic ulcer aggravated.

Could Acetaminophen and codeine phosphate cause Peptic ulcer aggravated?

Among these 51 people:

What is the gender of people who have Peptic ulcer aggravated when taking Acetaminophen and codeine phosphate? *

female: 71.74 %
male: 28.26 %

What is the age of people who have Peptic ulcer aggravated when taking Acetaminophen and codeine phosphate? *

What are other drugs people take besides Acetaminophen and codeine phosphate? *

Naproxen: 16 people, 31.37%
Lansoprazole: 15 people, 29.41%
Nitroglycerin: 15 people, 29.41%
Budesonide: 14 people, 27.45%
Fentanyl: 14 people, 27.45%
Pancuronium Bromide: 14 people, 27.45%
Propofol: 14 people, 27.45%
Quinine Sulfate: 14 people, 27.45%
Diltiazem Hydrochloride: 12 people, 23.53%
Atorvastatin Calcium: 11 people, 21.57%

What are other side effects people have besides Peptic ulcer aggravated? *

Haematemesis (vomiting of blood): 25 people, 49.02%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 23 people, 45.10%
Dizziness: 15 people, 29.41%
Acute Hepatic Failure: 14 people, 27.45%
Labile Blood Pressure (wildly fluctuating blood pressure): 14 people, 27.45%
Acute Kidney Failure: 14 people, 27.45%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 13 people, 25.49%
Melaena (the passage of black, tarry stools): 10 people, 19.61%
Haemoglobin Decreased: 8 people, 15.69%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 7 people, 13.73%

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 41.18%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 15 people, 29.41%
Asthma: 14 people, 27.45%
Muscle Spasms (muscle contraction): 12 people, 23.53%
High Blood Cholesterol: 12 people, 23.53%
Anaesthesia: 11 people, 21.57%
Depression: 9 people, 17.65%
Stable Angina (a constant chest pain): 7 people, 13.73%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 7 people, 13.73%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and codeine phosphate and have Peptic ulcer aggravated?

- Check whether Peptic ulcer aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen and codeine phosphate:

Acetaminophen and codeine phosphate (3,220 reports)

Peptic ulcer aggravated treatments and more:

Peptic ulcer aggravated (42 reports)

How severe was Peptic ulcer aggravated and when was it recovered:

Peptic ulcer aggravated in Acetaminophen and codeine phosphate

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Peptic ulcer aggravated and drugs with ingredients of acetaminophen; codeine phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and codeine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (1,488 drugs)

Browse all the conditions that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (545 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Acetaminophen and codeine phosphate) and Acetaminophen and codeine phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.