Acetaminophen and Adrenocortical insufficiency acute - a phase IV clinical study of FDA data

Summary:

Adrenocortical insufficiency acute is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Epinephrine, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Adrenocortical insufficiency acute when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Adrenocortical insufficiency acute?

Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones) is found to be associated with 230 drugs and 456 conditions by eHealthMe. Check the latest studies of Adrenocortical insufficiency acute.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 41 people (0.02%) have Adrenocortical insufficiency acute.

Could Acetaminophen cause Adrenocortical insufficiency acute?

Among these 41 people:

How long have people been on Acetaminophen when they have Adrenocortical insufficiency acute? *

What is the gender of people who have Adrenocortical insufficiency acute when taking Acetaminophen? *

female: 75.68 %
male: 24.32 %

What is the age of people who have Adrenocortical insufficiency acute when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

Epinephrine: 19 people, 46.34%
Dexamethasone: 18 people, 43.90%
Fluticasone Propionate: 12 people, 29.27%
Dicyclomine Hydrochloride: 12 people, 29.27%
Lansoprazole: 11 people, 26.83%
Enoxaparin Sodium: 11 people, 26.83%
Lactulose: 11 people, 26.83%
Doxazosin Mesylate: 9 people, 21.95%
Sodium Chloride: 9 people, 21.95%
Prednisone: 9 people, 21.95%

What are other side effects people have besides Adrenocortical insufficiency acute? *

Dehydration (dryness resulting from the removal of water): 13 people, 31.71%
Infusion Site Swelling: 12 people, 29.27%
Infusion Site Pain: 12 people, 29.27%
Infusion Site Pruritus (severe itching at infusion site): 12 people, 29.27%
Unilateral Hydronephrosis (kidney stone that causes obstruction of the ureter): 11 people, 26.83%
Haematuria (presence of blood in urine): 11 people, 26.83%
Staphylococcal Infection (an infection with staphylococcus bacteria): 11 people, 26.83%
Haemoglobin Decreased: 11 people, 26.83%
Sinusitis (inflammation of sinus): 11 people, 26.83%
Venous Thrombosis Limb (blood clot that forms in a vein in the limb): 11 people, 26.83%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 14 people, 34.15%
Asthma: 6 people, 14.63%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 5 people, 12.20%
Primary Immunodeficiency Syndrome: 3 people, 7.32%
Diffuse Large B-Cell Lymphoma Stage Ii (cancer of b cells, a type of white blood cell-stage ii): 3 people, 7.32%
Immune System Disorder: 2 people, 4.88%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 4.88%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Adrenocortical insufficiency acute?

- Check whether Adrenocortical insufficiency acute is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adrenocortical insufficiency acute:

Adrenocortical insufficiency acute (230 drugs)

Browse all the conditions that are associated with Adrenocortical insufficiency acute:

Adrenocortical insufficiency acute (456 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.