Acetaminophen and Amyotrophic lateral sclerosis - a phase IV clinical study of FDA data

Summary:

Amyotrophic lateral sclerosis is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Levothyroxine Sodium, and have Myasthenia gravis.

The phase IV clinical study analyzes which people have Amyotrophic lateral sclerosis when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Amyotrophic lateral sclerosis?

Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord) is found to be associated with 207 drugs and 531 conditions by eHealthMe. Check the latest studies of Amyotrophic lateral sclerosis.

On Jul, 20, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 13 people (0.01%) have Amyotrophic lateral sclerosis.

Could Acetaminophen cause Amyotrophic lateral sclerosis?

Among these 13 people:

How long have people been on Acetaminophen when they have Amyotrophic lateral sclerosis? *

What is the gender of people who have Amyotrophic lateral sclerosis when taking Acetaminophen? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Amyotrophic lateral sclerosis when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

What are other side effects people have besides Amyotrophic lateral sclerosis? *

Abdominal Pain: 2 people, 15.38%
Weakness: 2 people, 15.38%
Dyspnea (difficult or laboured breathing): 2 people, 15.38%
Liver Function Test Abnormal: 2 people, 15.38%
Nausea (feeling of having an urge to vomit): 2 people, 15.38%
Haematoma (collection of blood outside the blood vessels): 2 people, 15.38%
Swallowing Difficulty: 2 people, 15.38%
Muscle Aches (muscle pain): 2 people, 15.38%
Flat Affect (absence of emotional response to a situation): 1 person, 7.69%
Ear Pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear): 1 person, 7.69%

What are the existing conditions these people have? *

Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 3 people, 23.08%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Multifocal Motor Neuropathy (a progressively worsening condition where muscles in the extremities gradually weaken): 1 person, 7.69%
Ill-Defined Disorder: 1 person, 7.69%
High Blood Cholesterol: 1 person, 7.69%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 1 person, 7.69%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Amyotrophic lateral sclerosis?

- Check whether Amyotrophic lateral sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Amyotrophic lateral sclerosis:

Amyotrophic lateral sclerosis (207 drugs)

Browse all the conditions that are associated with Amyotrophic lateral sclerosis:

Amyotrophic lateral sclerosis (531 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.