Acetaminophen and Brain midline shift - a phase IV clinical study of FDA data

Summary:

Brain midline shift is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are male, 40-49 old, also take Zofran, and have Depression.

The phase IV clinical study analyzes which people have Brain midline shift when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Brain midline shift?

Brain midline shift is found to be associated with 86 drugs and 214 conditions by eHealthMe. Check the latest studies of Brain midline shift.

On Jul, 25, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 12 people (0.01%) have Brain midline shift.

Could Acetaminophen cause Brain midline shift?

Among these 12 people:

What is the gender of people who have Brain midline shift when taking Acetaminophen? *

female: 41.67 %
male: 58.33 %

What is the age of people who have Brain midline shift when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

What are other side effects people have besides Brain midline shift? *

Cerebral Haemorrhage (bleeding within the brain): 7 people, 58.33%
Insomnia (sleeplessness): 6 people, 50.00%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 6 people, 50.00%
Urinary Tract Infection: 6 people, 50.00%
Subdural Haematoma (blood collects between the skull and the surface of the brain): 6 people, 50.00%
Swallowing Difficulty: 5 people, 41.67%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 5 people, 41.67%
High Blood Pressure: 5 people, 41.67%
Sleep Apnea Syndrome: 5 people, 41.67%
Fall: 5 people, 41.67%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 3 people, 25.00%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Depression: 3 people, 25.00%
Birth Control: 2 people, 16.67%
Mood Swings (an extreme or rapid change in mood): 2 people, 16.67%
Thrombocytopenia (decrease of platelets in blood): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Arterial Disorder: 1 person, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Brain midline shift?

- Check whether Brain midline shift is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain midline shift:

Brain midline shift (86 drugs)

Browse all the conditions that are associated with Brain midline shift:

Brain midline shift (214 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.