Acetaminophen and Complement factor c4 decreased - a phase IV clinical study of FDA data

Summary:

Complement factor c4 decreased is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 60+ old, also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Complement factor c4 decreased when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Complement factor c4 decreased?

Complement factor c4 decreased is found to be associated with 36 drugs and 217 conditions by eHealthMe. Check the latest studies of Complement factor c4 decreased.

On Jul, 25, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 12 people (0.01%) have Complement factor c4 decreased.

Could Acetaminophen cause Complement factor c4 decreased?

Among these 12 people:

What is the gender of people who have Complement factor c4 decreased when taking Acetaminophen? *

female: 75 %
male: 25 %

What is the age of people who have Complement factor c4 decreased when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

Zopiclone: 10 people, 83.33%
Prednisone: 10 people, 83.33%
Methylprednisolone: 9 people, 75.00%
Darifenacin Hydrobromide: 9 people, 75.00%
Enbrel: 9 people, 75.00%
Hydroxychloroquine Sulfate: 9 people, 75.00%
Ibuprofen: 9 people, 75.00%
Melatonin: 9 people, 75.00%
Imitrex: 9 people, 75.00%
Pantoprazole: 9 people, 75.00%

What are other side effects people have besides Complement factor c4 decreased? *

Complement Factor C3 Decreased: 11 people, 91.67%
Haemoglobin Decreased: 11 people, 91.67%
Drug Ineffective: 10 people, 83.33%
Musculoskeletal Disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 9 people, 75.00%
Herpes Zoster: 9 people, 75.00%
Neuralgia (pain in one or more nerves): 9 people, 75.00%
Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 9 people, 75.00%
Osteopenia (a condition where bone mineral density is lower than normal): 9 people, 75.00%
Granulocyte Count Increased: 9 people, 75.00%
Mean Cell Haemoglobin Decreased (less than normal haemoglobin per red blood cell in a sample of blood): 9 people, 75.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 100.00%
Sleep Disorder: 6 people, 50.00%
Joint Pain: 1 person, 8.33%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 8.33%
Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Complement factor c4 decreased?

- Check whether Complement factor c4 decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Complement factor c4 decreased:

Complement factor c4 decreased (36 drugs)

Browse all the conditions that are associated with Complement factor c4 decreased:

Complement factor c4 decreased (217 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.