Acetaminophen and Joint lock - a phase IV clinical study of FDA data

Summary:

Joint lock is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Humira, and have Vasculitis.

The phase IV clinical study analyzes which people have Joint lock when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Joint lock?

Joint lock is found to be associated with 300 drugs and 490 conditions by eHealthMe. Check the latest studies of Joint lock.

On Jul, 14, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 33 people (0.02%) have Joint lock.

Among these 33 people:

How long have people been on Acetaminophen when they have Joint lock? *

What is the gender of people who have Joint lock when taking Acetaminophen? *

female: 80 %
male: 20 %

What is the age of people who have Joint lock when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

Humira: 18 people, 54.55%
Diphenhydramine Hydrochloride: 16 people, 48.48%
Methylprednisolone: 16 people, 48.48%
Ibuprofen: 13 people, 39.39%
Sulfasalazine: 12 people, 36.36%
Pantoprazole: 11 people, 33.33%
Methylprednisolone Sodium Succinate: 11 people, 33.33%
Folic Acid: 11 people, 33.33%
Tylenol: 11 people, 33.33%
Methotrexate: 11 people, 33.33%

What are other side effects people have besides Joint lock? *

Joint Pain: 22 people, 66.67%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 14 people, 42.42%
Joint Swelling: 13 people, 39.39%
Chest Pain: 12 people, 36.36%
Monocyte Count Increased: 11 people, 33.33%
Lymphocyte Count Decreased: 11 people, 33.33%
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 11 people, 33.33%
Weight Increased: 11 people, 33.33%
C-Reactive Protein Increased: 11 people, 33.33%
Blood Pressure Systolic Increased: 11 people, 33.33%

What are the existing conditions these people have? *

Vasculitis (inflammation of a blood vessel or blood vessels): 11 people, 33.33%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 18.18%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 15.15%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 9.09%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 9.09%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 2 people, 6.06%
Hypersensitivity: 2 people, 6.06%
High Blood Pressure: 2 people, 6.06%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 3.03%
Onychoclasis (breaking of the nails): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Joint lock?

- Check whether Joint lock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Joint lock treatments and more:

Joint lock (3,416 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint lock:

Joint lock (300 drugs)

Browse all the conditions that are associated with Joint lock:

Joint lock (490 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.