Acetaminophen and Ligament injury - a phase IV clinical study of FDA data

Summary:

Ligament injury is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Methylprednisolone, and have Muscle spasticity.

The phase IV clinical study analyzes which people have Ligament injury when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Ligament injury?

Ligament injury is found to be associated with 248 drugs and 331 conditions by eHealthMe. Check the latest studies of Ligament injury.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 42 people (0.02%) have Ligament injury.

Could Acetaminophen cause Ligament injury?

Among these 42 people:

How long have people been on Acetaminophen when they have Ligament injury? *

What is the gender of people who have Ligament injury when taking Acetaminophen? *

female: 85.37 %
male: 14.63 %

What is the age of people who have Ligament injury when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

What are other side effects people have besides Ligament injury? *

Fall: 32 people, 76.19%
Joint Pain: 21 people, 50.00%
Fatigue (feeling of tiredness): 19 people, 45.24%
Weakness: 17 people, 40.48%
Gait Disturbance: 16 people, 38.10%
Stress And Anxiety: 15 people, 35.71%
Nausea (feeling of having an urge to vomit): 15 people, 35.71%
Haemorrhage (bleeding): 15 people, 35.71%
Urticaria (rash of round, red welts on the skin that itch intensely): 14 people, 33.33%
Depression: 14 people, 33.33%

What are the existing conditions these people have? *

Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 11 people, 26.19%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 11 people, 26.19%
Stress And Anxiety: 8 people, 19.05%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 14.29%
Cardiac Disorder: 4 people, 9.52%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 4 people, 9.52%
Drowsiness: 3 people, 7.14%
Acute Myocardial Infarction (acute heart attack): 3 people, 7.14%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 7.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Ligament injury?

- Check whether Ligament injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Ligament injury treatments and more:

Ligament injury (1,649 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ligament injury:

Ligament injury (248 drugs)

Browse all the conditions that are associated with Ligament injury:

Ligament injury (331 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.