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Acetaminophen and Mean cell volume decreased - a phase IV clinical study of FDA data

Summary:

Mean cell volume decreased is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Crohn's disease.

The phase IV clinical study analyzes which people have Mean cell volume decreased when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Mean cell volume decreased?

Mean cell volume decreased (less of the average red blood cell volume) is found to be associated with 320 drugs and 426 conditions by eHealthMe. Check the latest studies of Mean cell volume decreased.

On Jul, 18, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 61 people (0.03%) have Mean cell volume decreased.

Could Acetaminophen cause Mean cell volume decreased?

Among these 61 people:

How long have people been on Acetaminophen when they have Mean cell volume decreased? *

  • < 1 month: 85.71 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 14.29 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Mean cell volume decreased when taking Acetaminophen? *

  • female: 75.61 %
  • male: 24.39 %

What is the age of people who have Mean cell volume decreased when taking Acetaminophen? *

  • 0-1: 5.41 %
  • 2-9: 5.41 %
  • 10-19: 8.11 %
  • 20-29: 10.81 %
  • 30-39: 18.92 %
  • 40-49: 10.81 %
  • 50-59: 13.51 %
  • 60+: 27.03 %

What are other drugs people take besides Acetaminophen? *

  1. Prednisone: 25 people, 40.98%
  2. Methylprednisolone Sodium Succinate: 15 people, 24.59%
  3. Methylprednisolone: 15 people, 24.59%
  4. Hydrocortisone: 14 people, 22.95%
  5. Benadryl: 12 people, 19.67%
  6. Sulfatrim: 12 people, 19.67%
  7. Gabapentin: 12 people, 19.67%
  8. Lasix: 11 people, 18.03%
  9. Synthroid: 11 people, 18.03%
  10. Pantoprazole: 11 people, 18.03%

What are other side effects people have besides Mean cell volume decreased? *

  1. Haemoglobin Decreased: 39 people, 63.93%
  2. Red Cell Distribution Width Increased: 26 people, 42.62%
  3. Haematocrit Decreased: 25 people, 40.98%
  4. Mean Cell Haemoglobin Decreased (less than normal haemoglobin per red blood cell in a sample of blood): 25 people, 40.98%
  5. Joint Pain: 22 people, 36.07%
  6. Mean Cell Haemoglobin Concentration Decreased (less concentration of haemoglobin in a given volume of packed red blood cells): 18 people, 29.51%
  7. High Blood Pressure: 17 people, 27.87%
  8. Weight Decreased: 16 people, 26.23%
  9. Urinary Tract Infection: 15 people, 24.59%
  10. Malaise (a feeling of general discomfort or uneasiness): 14 people, 22.95%

What are the existing conditions these people have? *

  1. Vasculitis (inflammation of a blood vessel or blood vessels): 8 people, 13.11%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 8 people, 13.11%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 8.20%
  4. Gout (uric acid crystals building up in the body): 4 people, 6.56%
  5. Canker Sores (painful, open sore in the mouth): 4 people, 6.56%
  6. Migraine (headache): 3 people, 4.92%
  7. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 4.92%
  8. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 4.92%
  9. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 3 people, 4.92%
  10. Depression: 3 people, 4.92%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Mean cell volume decreased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Mean cell volume decreased treatments and more:

How severe was Mean cell volume decreased and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mean cell volume decreased:

Browse all the conditions that are associated with Mean cell volume decreased:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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