Acetaminophen and Pitting oedema - a phase IV clinical study of FDA data

Summary:

Pitting oedema is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are male, 60+ old, also take Furosemide, and have Blood phosphorus increased.

The phase IV clinical study analyzes which people have Pitting oedema when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,078 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Pitting oedema?

Pitting oedema (skin discoloration) is found to be associated with 241 drugs and 421 conditions by eHealthMe. Check the latest studies of Pitting oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 35 people (0.02%) have Pitting oedema.

Could Acetaminophen cause Pitting oedema?

Among these 35 people:

What is the gender of people who have Pitting oedema when taking Acetaminophen? *

female: 48.57 %
male: 51.43 %

What is the age of people who have Pitting oedema when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

What are other side effects people have besides Pitting oedema? *

Oedema Peripheral (superficial swelling): 13 people, 37.14%
Pleural Effusion (water on the lungs): 12 people, 34.29%
Acute Kidney Failure: 11 people, 31.43%
Nausea (feeling of having an urge to vomit): 9 people, 25.71%
Weight Increased: 9 people, 25.71%
Stress And Anxiety: 9 people, 25.71%
Fatigue (feeling of tiredness): 9 people, 25.71%
Fall: 8 people, 22.86%
High Blood Pressure: 8 people, 22.86%
Thrombocytopenia (decrease of platelets in blood): 8 people, 22.86%

What are the existing conditions these people have? *

Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 3 people, 8.57%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 3 people, 8.57%
Blood Phosphorus Increased: 3 people, 8.57%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 5.71%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 5.71%
Type 2 Diabetes: 1 person, 2.86%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.86%
Ovarian Cancer (cancer of ovary): 1 person, 2.86%
Nuclear Magnetic Resonance Imaging Abdominal: 1 person, 2.86%
Neuralgia (pain in one or more nerves): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Pitting oedema?

- Check whether Pitting oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,078 reports)

Pitting oedema treatments and more:

Pitting oedema (1,300 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pitting oedema:

Pitting oedema (241 drugs)

Browse all the conditions that are associated with Pitting oedema:

Pitting oedema (421 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.