Acetaminophen and Postoperative ileus - a phase IV clinical study of FDA data

Summary:

Postoperative ileus is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Prednisone, and have Crohn's disease.

The phase IV clinical study analyzes which people have Postoperative ileus when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Postoperative ileus?

Postoperative ileus is found to be associated with 153 drugs and 271 conditions by eHealthMe. Check the latest studies of Postoperative ileus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 23 people (0.01%) have Postoperative ileus.

Could Acetaminophen cause Postoperative ileus?

Among these 23 people:

How long have people been on Acetaminophen when they have Postoperative ileus? *

What is the gender of people who have Postoperative ileus when taking Acetaminophen? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Postoperative ileus when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

What are other side effects people have besides Postoperative ileus? *

Abdominal Pain: 4 people, 17.39%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 4 people, 17.39%
Rashes (redness): 4 people, 17.39%
Gastrointestinal Stoma Complication (complication of an opening surgically made in digestive tract): 4 people, 17.39%
Nausea And Vomiting: 4 people, 17.39%
Abdominal Distension: 3 people, 13.04%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 13.04%
Hypokalemia (low potassium): 3 people, 13.04%
Gastroenteritis Viral (inflammation of stomach and intestine caused by virus infection): 2 people, 8.70%
Lower Respiratory Tract Infection: 2 people, 8.70%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 30.43%
Ill-Defined Disorder: 5 people, 21.74%
Parkinson's Disease: 3 people, 13.04%
Multiple Myeloma (cancer of the plasma cells): 3 people, 13.04%
Incision Site Pain: 3 people, 13.04%
Immunodeficiency: 2 people, 8.70%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 8.70%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.35%
Osteoporosis (bones weak and more likely to break): 1 person, 4.35%
Laryngeal Cancer Stage Iii (cancer may have spread to lymph node on same side): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Postoperative ileus?

- Check whether Postoperative ileus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,077 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Postoperative ileus:

Postoperative ileus (153 drugs)

Browse all the conditions that are associated with Postoperative ileus:

Postoperative ileus (271 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.