Acetaminophen and Uc - a phase IV clinical study of FDA data

Summary:

Uc is reported as a side effect among people who take Acetaminophen (acetaminophen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Crohn's disease.

The phase IV clinical study analyzes which people have Uc when taking Acetaminophen. It is created by eHealthMe based on reports of 181,086 people who have side effects when taking Acetaminophen from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,070 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Uc?

Uc is found to be associated with 1,329 drugs and 2,013 conditions by eHealthMe. Check the latest studies of Uc.

On Oct, 20, 2025

181,086 people reported to have side effects when taking Acetaminophen.
Among them, 887 people (0.49%) have Uc.

Among these 887 people:

How long have people been on Acetaminophen when they have Uc? *

What is the gender of people who have Uc when taking Acetaminophen? *

female: 74.34 %
male: 25.66 %

What is the age of people who have Uc when taking Acetaminophen? *

What are other drugs people take besides Acetaminophen? *

What are other side effects people have besides Uc? *

Diarrhea: 490 people, 55.24%
Rectal Haemorrhage (bleeding from anus): 421 people, 47.46%
Fever: 388 people, 43.74%
Abdominal Pain: 377 people, 42.50%
Rashes (redness): 358 people, 40.36%
Nausea (feeling of having an urge to vomit): 336 people, 37.88%
Haematochezia (passage of stools containing blood): 322 people, 36.30%
Weight Decreased: 318 people, 35.85%
Drug Ineffective: 308 people, 34.72%
Constipation: 307 people, 34.61%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 238 people, 26.83%
Colitis (inflammation of colon): 123 people, 13.87%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 95 people, 10.71%
Allergies: 94 people, 10.60%
Fever: 81 people, 9.13%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 70 people, 7.89%
Acne (skin problems that cause pimples): 65 people, 7.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 63 people, 7.10%
Nausea (feeling of having an urge to vomit): 57 people, 6.43%
High Blood Pressure: 56 people, 6.31%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and have Uc?

- Check whether Uc is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen:

Acetaminophen (183,070 reports)

Uc treatments and more:

Uc (188,229 reports)

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Uc:

Prednisone side effect: Uc (9,847 reports)
Accutane side effect: Uc (9,193 reports)
Humira side effect: Uc (7,275 reports)
Mesalamine side effect: Uc (4,332 reports)
Remicade side effect: Uc (4,272 reports)
Entyvio side effect: Uc (2,464 reports)
Methotrexate side effect: Uc (2,260 reports)
Asacol side effect: Uc (1,994 reports)
Pentasa side effect: Uc (1,864 reports)
Pantoprazole side effect: Uc (1,708 reports)

Browse all the drugs that are associated with Uc:

Uc (1,327 drugs)

Common conditions associated with Uc:

Uc: 9,507 reports
Acne aggravated: 6,047 reports
Zits: 6,041 reports
Ulcerative colitis: 4,538 reports
Inflammatory bowel disease - ulcerative colitis: 4,525 reports
Colitis ulcerative: 3,853 reports
Granulomatous ileocolitis: 1,997 reports
Blood pressure - high: 1,314 reports
Rheumatoid arthritis: 1,295 reports
Multiple sclerosis: 765 reports

Browse all the conditions that are associated with Uc:

Uc (2,013 conditions)

Drugs similar to Acetaminophen and Uc :

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acetaminophen) and Acetaminophen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.