Akineton and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Akineton (biperiden hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Seroquel, and have Schizophrenia.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Akineton. It is created by eHealthMe based on reports of 6,101 people who have side effects when taking Akineton from the FDA, and is updated regularly.

What is Akineton?

Akineton has active ingredients of biperiden hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 6,140 Akineton users. Check the latest studies of Akineton.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,544 drugs and 1,943 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

On Nov, 30, 2025

6,101 people reported to have side effects when taking Akineton.
Among them, 16 people (0.26%) have Liver function test abnormal.

Could Akineton cause Liver function test abnormal?

Among these 16 people:

How long have people been on Akineton when they have Liver function test abnormal? *

What is the gender of people who have Liver function test abnormal when taking Akineton? *

female: 31.25 %
male: 68.75 %

What is the age of people who have Liver function test abnormal when taking Akineton? *

What are other drugs people take besides Akineton? *

What are other side effects people have besides Liver function test abnormal? *

Fever: 5 people, 31.25%
Blood Creatine Phosphokinase Increased: 5 people, 31.25%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 3 people, 18.75%
Leukocytosis (increased white blood cells): 3 people, 18.75%
Oedema Peripheral (superficial swelling): 3 people, 18.75%
White Blood Cell Count Increased: 2 people, 12.50%
Blood Creatine Phosphokinase Decreased: 2 people, 12.50%
High Blood Pressure: 2 people, 12.50%
Myoglobin Blood Increased (presence of myoglobin in blood increased): 2 people, 12.50%
C-Reactive Protein Increased: 2 people, 12.50%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 25.00%
Insomnia (sleeplessness): 3 people, 18.75%
Schizophrenia, Disorganised Type (speech and behaviour that are disorganized or difficult to understand): 3 people, 18.75%
High Blood Pressure: 2 people, 12.50%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 12.50%
Nasopharyngitis (inflammation of the nasopharynx): 2 people, 12.50%
Constipation: 2 people, 12.50%
Diabetes: 2 people, 12.50%
Depression: 1 person, 6.25%
Back Pain: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Akineton and have Liver function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Akineton:

Akineton (6,140 reports)

Browse all side effects of Akineton:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver function test abnormal:

Liver function test abnormal (1,544 drugs)

Browse all the conditions that are associated with Liver function test abnormal:

Liver function test abnormal (1,943 conditions)

Drugs similar to Akineton and Liver function test abnormal :

How the study uses the data?

The study uses data from the FDA. It is based on biperiden hydrochloride (the active ingredients of Akineton) and Akineton (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.