Allopurinol and Urine protein/creatinine ratio increased - a phase IV clinical study of FDA data

Summary:

Urine protein/creatinine ratio increased is reported as a side effect among people who take Allopurinol (allopurinol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Tegsedi, and have Hereditary neuropathic amyloidosis.

The phase IV clinical study analyzes which people have Urine protein/creatinine ratio increased when taking Allopurinol. It is created by eHealthMe based on reports of 188,106 people who have side effects when taking Allopurinol from the FDA, and is updated regularly.

What is Allopurinol?

Allopurinol has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,868 Allopurinol users. Check the latest studies of Allopurinol.

What is Urine protein/creatinine ratio increased?

Urine protein/creatinine ratio increased is found to be associated with 99 drugs and 198 conditions by eHealthMe. Check the latest studies of Urine protein/creatinine ratio increased.

On Jul, 06, 2026

188,106 people reported to have side effects when taking Allopurinol.
Among them, 28 people (0.01%) have Urine protein/creatinine ratio increased.

Could Allopurinol cause Urine protein/creatinine ratio increased?

Among these 28 people:

How long have people been on Allopurinol when they have Urine protein/creatinine ratio increased? *

What is the gender of people who have Urine protein/creatinine ratio increased when taking Allopurinol? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Urine protein/creatinine ratio increased when taking Allopurinol? *

What are other drugs people take besides Allopurinol? *

What are other side effects people have besides Urine protein/creatinine ratio increased? *

Blood Creatinine Increased: 17 people, 60.71%
Glomerular Filtration Rate Decreased: 16 people, 57.14%
Thrombocytopenia (decrease of platelets in blood): 14 people, 50.00%
Haematocrit Decreased: 12 people, 42.86%
Haemoglobin Decreased: 12 people, 42.86%
Protein Urine Present: 12 people, 42.86%
White Blood Cells Urine Positive: 11 people, 39.29%
Fall: 11 people, 39.29%
Oedema Peripheral (superficial swelling): 11 people, 39.29%
Bacterial Test Positive: 10 people, 35.71%

What are the existing conditions these people have? *

Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 17 people, 60.71%
Pain: 7 people, 25.00%
High Blood Pressure: 5 people, 17.86%
Type 2 Diabetes: 3 people, 10.71%
Renal Cell Carcinoma (a kidney cancer): 3 people, 10.71%
Muscle Spasms (muscle contraction): 3 people, 10.71%
Magnesium Deficiency (lack of magnesium): 2 people, 7.14%
Blood Uric Acid Increased: 2 people, 7.14%
Cardiac Disorder: 2 people, 7.14%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Allopurinol and have Urine protein/creatinine ratio increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Allopurinol:

Allopurinol (190,868 reports)

Urine protein/creatinine ratio increased treatments and more:

Urine protein/creatinine ratio increased (977 reports)

How severe was Urine protein/creatinine ratio increased and when was it recovered:

Urine protein/creatinine ratio increased in Allopurinol

Expand to all the drugs that have ingredients of allopurinol:

Urine protein/creatinine ratio increased and drugs with ingredients of allopurinol (31 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Allopurinol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urine protein/creatinine ratio increased:

Urine protein/creatinine ratio increased (99 drugs)

Browse all the conditions that are associated with Urine protein/creatinine ratio increased:

Urine protein/creatinine ratio increased (198 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on allopurinol (the active ingredients of Allopurinol) and Allopurinol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.