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Ambien and Intestinal ischaemia - a phase IV clinical study of FDA data

Summary:

Intestinal ischaemia is reported as a side effect among people who take Ambien (zolpidem tartrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Intestinal ischaemia when taking Ambien. It is created by eHealthMe based on reports of 86,763 people who have side effects when taking Ambien from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Intestinal ischaemia?

Intestinal ischaemia (decreased supply of oxygenated blood to the intestines) is found to be associated with 675 drugs and 833 conditions by eHealthMe. Check the latest studies of Intestinal ischaemia.

On Aug, 07, 2026

86,763 people reported to have side effects when taking Ambien.
Among them, 48 people (0.06%) have Intestinal ischaemia.

Could Ambien cause Intestinal ischaemia?

Among these 48 people:

How long have people been on Ambien when they have Intestinal ischaemia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Intestinal ischaemia when taking Ambien? *

  • female: 60.47 %
  • male: 39.53 %

What is the age of people who have Intestinal ischaemia when taking Ambien? *

  • 0-1: 10.26 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.13 %
  • 40-49: 7.69 %
  • 50-59: 10.26 %
  • 60+: 66.67 %

What are other drugs people take besides Ambien? *

  1. Zofran: 11 people, 22.92%
  2. Neurontin: 10 people, 20.83%
  3. Coumadin: 10 people, 20.83%
  4. Aspirin: 7 people, 14.58%
  5. Norvasc: 7 people, 14.58%
  6. Lisinopril: 7 people, 14.58%
  7. Protonix: 7 people, 14.58%
  8. Nitroglycerin: 6 people, 12.50%
  9. Lasix: 6 people, 12.50%
  10. Lipitor: 6 people, 12.50%

What are other side effects people have besides Intestinal ischaemia? *

  1. Diarrhea: 17 people, 35.42%
  2. Hypotension (abnormally low blood pressure): 16 people, 33.33%
  3. Abdominal Pain: 14 people, 29.17%
  4. Acute Kidney Failure: 14 people, 29.17%
  5. Dyspnea (difficult or laboured breathing): 12 people, 25.00%
  6. Pain: 11 people, 22.92%
  7. Nausea (feeling of having an urge to vomit): 11 people, 22.92%
  8. Anaemia (lack of blood): 11 people, 22.92%
  9. Thrombocytopenia (decrease of platelets in blood): 11 people, 22.92%
  10. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 11 people, 22.92%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 16.67%
  2. Pain: 4 people, 8.33%
  3. High Blood Pressure: 4 people, 8.33%
  4. Multiple Myeloma (cancer of the plasma cells): 4 people, 8.33%
  5. Nausea (feeling of having an urge to vomit): 4 people, 8.33%
  6. Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 6.25%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.25%
  8. High Blood Cholesterol: 3 people, 6.25%
  9. Neuropathy Peripheral (surface nerve damage): 3 people, 6.25%
  10. Anaemia (lack of blood): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ambien and have Intestinal ischaemia?

- Check whether Intestinal ischaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambien:

Intestinal ischaemia treatments and more:

How severe was Intestinal ischaemia and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal ischaemia:

Browse all the conditions that are associated with Intestinal ischaemia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Ambien) and Ambien (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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