Ambrisentan and Toothaches - a phase IV clinical study of FDA data

Summary:

Toothaches is reported as a side effect among people who take Ambrisentan (ambrisentan), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Uptravi, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Toothaches when taking Ambrisentan. It is created by eHealthMe based on reports of 61,294 people who have side effects when taking Ambrisentan from the FDA, and is updated regularly.

What is Ambrisentan?

Ambrisentan has active ingredients of ambrisentan. eHealthMe is studying from 61,368 Ambrisentan users. Check the latest studies of Ambrisentan.

What is Toothaches?

Toothaches (tooth pain) is found to be associated with 1,318 drugs and 1,605 conditions by eHealthMe. Check the latest studies of Toothaches.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 29, 2026

61,294 people reported to have side effects when taking Ambrisentan.
Among them, 87 people (0.14%) have Toothaches.

Could Ambrisentan cause Toothaches?

Among these 87 people:

How long have people been on Ambrisentan when they have Toothaches? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Toothaches when taking Ambrisentan? *

  • female: 82.76 %
  • male: 17.24 %

What is the age of people who have Toothaches when taking Ambrisentan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.56 %
  • 30-39: 8.33 %
  • 40-49: 5.56 %
  • 50-59: 25.0 %
  • 60+: 55.56 %

What are other drugs people take besides Ambrisentan? *

  1. Uptravi: 40 people, 45.98%
  2. Adcirca: 31 people, 35.63%
  3. Tyvaso: 13 people, 14.94%
  4. Revatio: 12 people, 13.79%
  5. Lasix: 9 people, 10.34%
  6. Adempas: 9 people, 10.34%
  7. Spiriva: 9 people, 10.34%
  8. Lipitor: 7 people, 8.05%
  9. Tadalafil: 7 people, 8.05%
  10. Wellbutrin: 7 people, 8.05%

What are other side effects people have besides Toothaches? *

  1. Headache (pain in head): 47 people, 54.02%
  2. Dyspnea (difficult or laboured breathing): 32 people, 36.78%
  3. Pain In Jaw: 30 people, 34.48%
  4. Diarrhea: 27 people, 31.03%
  5. Fatigue (feeling of tiredness): 26 people, 29.89%
  6. Chest Pain: 26 people, 29.89%
  7. Pain In Extremity: 25 people, 28.74%
  8. Pain: 24 people, 27.59%
  9. Cough: 23 people, 26.44%
  10. Malaise (a feeling of general discomfort or uneasiness): 20 people, 22.99%

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 49 people, 56.32%
  2. Pulmonary Hypertension (increase in blood pressure in the lung artery): 22 people, 25.29%
  3. Pharyngitis Streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 4 people, 4.60%
  4. Oral Candidiasis (fungal infection of mouth): 4 people, 4.60%
  5. Multiple Allergies (allergy to multiple agents): 4 people, 4.60%
  6. Infection: 4 people, 4.60%
  7. Ear Pain: 2 people, 2.30%
  8. Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 1.15%
  9. Pulmonary Oedema (fluid accumulation in the lungs): 1 person, 1.15%
  10. Pain In Extremity: 1 person, 1.15%

* Approximation only. Some reports may have incomplete information.

Do you take Ambrisentan and have Toothaches?

- Check whether Toothaches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ambrisentan:

Toothaches treatments and more:

How severe was Toothaches and when was it recovered:

Expand to all the drugs that have ingredients of ambrisentan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambrisentan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toothaches:

Browse all the conditions that are associated with Toothaches:


How the study uses the data?

The study uses data from the FDA. It is based on ambrisentan (the active ingredients of Ambrisentan) and Ambrisentan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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