Amlodipine and Spondylolisthesis - a phase IV clinical study of FDA data

Summary:

Spondylolisthesis is reported as a side effect among people who take Amlodipine (amlodipine besylate), especially for people who are female, 60+ old, also take Lisinopril, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Spondylolisthesis when taking Amlodipine. It is created by eHealthMe based on reports of 346,875 people who have side effects when taking Amlodipine from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,830 Amlodipine users. Check the latest studies of Amlodipine.

What is Spondylolisthesis?

Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below) is found to be associated with 565 drugs and 493 conditions by eHealthMe. Check the latest studies of Spondylolisthesis.



On Aug, 10, 2026

346,875 people reported to have side effects when taking Amlodipine.
Among them, 61 people (0.02%) have Spondylolisthesis.

Could Amlodipine cause Spondylolisthesis?

Among these 61 people:

What is the gender of people who have Spondylolisthesis when taking Amlodipine? *

  • female: 72.22 %
  • male: 27.78 %

What is the age of people who have Spondylolisthesis when taking Amlodipine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.33 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 4.65 %
  • 50-59: 9.3 %
  • 60+: 83.72 %

What are other drugs people take besides Amlodipine? *

  1. Lisinopril: 13 people, 21.31%
  2. Kisqali: 9 people, 14.75%
  3. Levothyroxine Sodium: 8 people, 13.11%
  4. Norvasc: 8 people, 13.11%
  5. Aspirin: 7 people, 11.48%
  6. Vitamin D3: 7 people, 11.48%
  7. Tylenol: 7 people, 11.48%
  8. Folic Acid: 7 people, 11.48%
  9. Humira: 6 people, 9.84%
  10. Fosamax: 6 people, 9.84%

What are other side effects people have besides Spondylolisthesis? *

  1. Back Pain: 26 people, 42.62%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 22 people, 36.07%
  3. Pain: 21 people, 34.43%
  4. Intervertebral Disc Degeneration (spinal disc degeneration): 19 people, 31.15%
  5. Fall: 18 people, 29.51%
  6. Swallowing Difficulty: 16 people, 26.23%
  7. Anaemia (lack of blood): 14 people, 22.95%
  8. Oedema (fluid collection in tissue): 13 people, 21.31%
  9. Spinal Osteoarthritis (joint cartilage loss in spine): 13 people, 21.31%
  10. Rickets (softening of bones): 12 people, 19.67%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 16.39%
  2. High Blood Cholesterol: 9 people, 14.75%
  3. Breast Cancer: 9 people, 14.75%
  4. Primary Hypothyroidism (failure of the thyroid gland to produce or release thyroid hormones into the bloodstream): 8 people, 13.11%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.84%
  6. Pain: 6 people, 9.84%
  7. Bone Disorder: 6 people, 9.84%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 8.20%
  9. Thyroid Diseases: 5 people, 8.20%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine and have Spondylolisthesis?

- Check whether Spondylolisthesis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amlodipine:

Spondylolisthesis treatments and more:

How severe was Spondylolisthesis and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spondylolisthesis:

Browse all the conditions that are associated with Spondylolisthesis:


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Amlodipine) and Amlodipine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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