Amoxicillin and clavulanate potassium and Corneal dystrophy - a phase IV clinical study of FDA data

Summary:

Corneal dystrophy is reported as a side effect among people who take Amoxicillin and clavulanate potassium (amoxicillin; clavulanate potassium), especially for people who are female, 60+ old, also take Furosemide, and have Osteoporosis.

The phase IV clinical study analyzes which people have Corneal dystrophy when taking Amoxicillin and clavulanate potassium. It is created by eHealthMe based on reports of 5,976 people who have side effects when taking Amoxicillin and clavulanate potassium from the FDA, and is updated regularly.

What is Amoxicillin and clavulanate potassium?

Amoxicillin and clavulanate potassium has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 6,181 Amoxicillin and clavulanate potassium users. Check the latest studies of Amoxicillin and clavulanate potassium.

What is Corneal dystrophy?

Corneal dystrophy (abnormal deposition of substances in the transparent front part of the eye) is found to be associated with 132 drugs and 45 conditions by eHealthMe. Check the latest studies of Corneal dystrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

5,976 people reported to have side effects when taking Amoxicillin and clavulanate potassium.
Among them, 13 people (0.22%) have Corneal dystrophy.

Could Amoxicillin and clavulanate potassium cause Corneal dystrophy?

Among these 13 people:

What is the gender of people who have Corneal dystrophy when taking Amoxicillin and clavulanate potassium? *

female: 100 %
male: 0.0 %

What is the age of people who have Corneal dystrophy when taking Amoxicillin and clavulanate potassium? *

What are other drugs people take besides Amoxicillin and clavulanate potassium? *

What are other side effects people have besides Corneal dystrophy? *

Wound Infection Pseudomonas: 13 people, 100.00%
Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 100.00%
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein): 13 people, 100.00%
Melanosis Coli (a condition that can be caused from chronic laxative abuse): 13 people, 100.00%
Joint Dislocation (a joint position is changed from normal position): 13 people, 100.00%
Itching: 13 people, 100.00%
Intertrigo (inflammation (rash) of the body folds (adjacent areas of skin)): 13 people, 100.00%
Weight Loss: 13 people, 100.00%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 13 people, 100.00%
Glare (difficulty seeing in the presence of bright light): 13 people, 100.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 13 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxicillin and clavulanate potassium and have Corneal dystrophy?

- Check whether Corneal dystrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amoxicillin and clavulanate potassium:

Amoxicillin and clavulanate potassium (6,181 reports)

Corneal dystrophy treatments and more:

Corneal dystrophy (709 reports)

How severe was Corneal dystrophy and when was it recovered:

Corneal dystrophy in Amoxicillin and clavulanate potassium

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Corneal dystrophy and drugs with ingredients of amoxicillin; clavulanate potassium

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amoxicillin and clavulanate potassium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Corneal dystrophy:

Corneal dystrophy (132 drugs)

Browse all the conditions that are associated with Corneal dystrophy:

Corneal dystrophy (45 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Amoxicillin and clavulanate potassium) and Amoxicillin and clavulanate potassium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.