Amoxicillin and Sigmoiditis - a phase IV clinical study of FDA data

Summary:

Sigmoiditis is reported as a side effect among people who take Amoxicillin (amoxicillin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Bone density abnormal.

The phase IV clinical study analyzes which people have Sigmoiditis when taking Amoxicillin. It is created by eHealthMe based on reports of 95,831 people who have side effects when taking Amoxicillin from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Sigmoiditis?

Sigmoiditis (inflammation of the sigmoid colon) is found to be associated with 61 drugs and 156 conditions by eHealthMe. Check the latest studies of Sigmoiditis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

95,831 people reported to have side effects when taking Amoxicillin.
Among them, 20 people (0.02%) have Sigmoiditis.

Among these 20 people:

How long have people been on Amoxicillin when they have Sigmoiditis? *

What is the gender of people who have Sigmoiditis when taking Amoxicillin? *

female: 15.79 %
male: 84.21 %

What is the age of people who have Sigmoiditis when taking Amoxicillin? *

What are other drugs people take besides Amoxicillin? *

Zometa: 11 people, 55.00%
Lexapro: 10 people, 50.00%
Casodex: 10 people, 50.00%
Lupron: 10 people, 50.00%
Ibuprofen: 10 people, 50.00%
Medrol: 10 people, 50.00%
Hyzaar: 10 people, 50.00%
Florinef: 10 people, 50.00%
Flonase: 10 people, 50.00%
Midodrine Hydrochloride: 10 people, 50.00%

What are other side effects people have besides Sigmoiditis? *

Joint Pain: 12 people, 60.00%
Back Pain: 12 people, 60.00%
Bone Disorder: 12 people, 60.00%
Chest Pain: 11 people, 55.00%
Headache (pain in head): 11 people, 55.00%
Pain: 11 people, 55.00%
High Blood Cholesterol: 11 people, 55.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 55.00%
Fatigue (feeling of tiredness): 11 people, 55.00%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 11 people, 55.00%

What are the existing conditions these people have? *

Prostate Cancer: 10 people, 50.00%
Pain: 10 people, 50.00%
Bone Density Abnormal: 10 people, 50.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 10.00%
Hepatitis C: 2 people, 10.00%
Osteitis (a general term for inflammation of bone): 1 person, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%
Constipation: 1 person, 5.00%
Back Pain: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxicillin and have Sigmoiditis?

- Check whether Sigmoiditis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Amoxicillin:

Amoxicillin (99,235 reports)

Sigmoiditis treatments and more:

Sigmoiditis (366 reports)

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sigmoiditis:

Sigmoiditis (61 drugs)

Browse all the conditions that are associated with Sigmoiditis:

Sigmoiditis (156 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin (the active ingredients of Amoxicillin) and Amoxicillin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.