Aranesp and Dental necrosis - a phase IV clinical study of FDA data

Summary:

Dental necrosis is reported as a side effect among people who take Aranesp (darbepoetin alfa), especially for people who are female, 60+ old, also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Dental necrosis when taking Aranesp. It is created by eHealthMe based on reports of 54,218 people who have side effects when taking Aranesp from the FDA, and is updated regularly.

What is Aranesp?

Aranesp has active ingredients of darbepoetin alfa. It is often used in anemia. eHealthMe is studying from 54,331 Aranesp users. Check the latest studies of Aranesp.

What is Dental necrosis?

Dental necrosis (tissue inside a tooth dies) is found to be associated with 90 drugs and 154 conditions by eHealthMe. Check the latest studies of Dental necrosis.

On Jul, 18, 2026

54,218 people reported to have side effects when taking Aranesp.
Among them, 14 people (0.03%) have Dental necrosis.

Among these 14 people:

What is the gender of people who have Dental necrosis when taking Aranesp? *

female: 92.86 %
male: 7.14 %

What is the age of people who have Dental necrosis when taking Aranesp? *

What are other drugs people take besides Aranesp? *

What are other side effects people have besides Dental necrosis? *

Back Pain: 12 people, 85.71%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 12 people, 85.71%
Multiple Myeloma (cancer of the plasma cells): 12 people, 85.71%
Infection: 12 people, 85.71%
Injury: 12 people, 85.71%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 12 people, 85.71%
Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 12 people, 85.71%
Fever: 12 people, 85.71%
Stress And Anxiety: 12 people, 85.71%
Pleural Effusion (water on the lungs): 12 people, 85.71%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 2 people, 14.29%
Pain: 1 person, 7.14%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%
Limb Discomfort (discomfort in leg): 1 person, 7.14%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 7.14%
Breast Cancer: 1 person, 7.14%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 7.14%
Acute Kidney Failure: 1 person, 7.14%
Acne (skin problems that cause pimples): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Aranesp and have Dental necrosis?

- Check whether Dental necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aranesp:

Aranesp (54,331 reports)

Browse all side effects of Aranesp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dental necrosis:

Dental necrosis (90 drugs)

Browse all the conditions that are associated with Dental necrosis:

Dental necrosis (154 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on darbepoetin alfa (the active ingredients of Aranesp) and Aranesp (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.