Arixtra and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Arixtra (fondaparinux sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Sutent, and have Thrombophlebitis.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Arixtra. It is created by eHealthMe based on reports of 9,755 people who have side effects when taking Arixtra from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,042 drugs and 1,781 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.

On Jul, 06, 2026

9,755 people reported to have side effects when taking Arixtra.
Among them, 17 people (0.17%) have Clostridium difficile colitis.

Could Arixtra cause Clostridium difficile colitis?

Among these 17 people:

How long have people been on Arixtra when they have Clostridium difficile colitis? *

What is the gender of people who have Clostridium difficile colitis when taking Arixtra? *

female: 58.82 %
male: 41.18 %

What is the age of people who have Clostridium difficile colitis when taking Arixtra? *

What are other drugs people take besides Arixtra? *

Sutent: 5 people, 29.41%
Esomeprazole Magnesium: 3 people, 17.65%
Xanax: 3 people, 17.65%
Atenolol: 3 people, 17.65%
Ativan: 3 people, 17.65%
Nicardipine Hydrochloride: 3 people, 17.65%
Irbesartan: 3 people, 17.65%
Zofran: 3 people, 17.65%
Hydrocortisone: 3 people, 17.65%
Hydroxyzine: 2 people, 11.76%

What are other side effects people have besides Clostridium difficile colitis? *

Dehydration (dryness resulting from the removal of water): 10 people, 58.82%
Hypotension (abnormally low blood pressure): 6 people, 35.29%
Septic Shock (shock due to blood infection): 6 people, 35.29%
Hyperkalemia (damage to or disease of the kidney): 5 people, 29.41%
Pancreatitis Acute (sudden inflammation of pancreas): 5 people, 29.41%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 5 people, 29.41%
Anastomotic Fistula: 5 people, 29.41%
Enterococcal Bacteraemia (presence of bacteria lactic acid in the blood): 5 people, 29.41%
General Physical Health Deterioration (weak health status): 5 people, 29.41%
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 5 people, 29.41%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 29.41%
Indigestion: 5 people, 29.41%
High Blood Pressure: 5 people, 29.41%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 5 people, 29.41%
Renal Cell Carcinoma (a kidney cancer): 5 people, 29.41%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 5 people, 29.41%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 11.76%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 1 person, 5.88%
Neoplasm Malignant (cancer tumour): 1 person, 5.88%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Arixtra and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Arixtra:

Arixtra (9,830 reports)

Browse all side effects of Arixtra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,042 drugs)

Browse all the conditions that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,781 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fondaparinux sodium (the active ingredients of Arixtra) and Arixtra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.