1. Home
  2. Analysis
  3. Augmentin
  4. Multiple-sclerosis

Augmentin and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Augmentin (amoxicillin; clavulanate potassium), especially for people who are female, 50-59 old, also take Neurontin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Augmentin. It is created by eHealthMe based on reports of 41,293 people who have side effects when taking Augmentin from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,088 drugs and 1,359 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

On Jul, 16, 2026

41,293 people reported to have side effects when taking Augmentin.
Among them, 51 people (0.12%) have Multiple sclerosis.

Could Augmentin cause Multiple sclerosis?

Among these 51 people:

What is the gender of people who have Multiple sclerosis when taking Augmentin? *

  • female: 74.51 %
  • male: 25.49 %

What is the age of people who have Multiple sclerosis when taking Augmentin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.67 %
  • 30-39: 11.11 %
  • 40-49: 24.44 %
  • 50-59: 46.67 %
  • 60+: 11.11 %

What are other drugs people take besides Augmentin? *

  1. Neurontin: 27 people, 52.94%
  2. Cipro: 24 people, 47.06%
  3. Zometa: 20 people, 39.22%
  4. Aredia: 19 people, 37.25%
  5. Celebrex: 18 people, 35.29%
  6. Plaquenil: 18 people, 35.29%
  7. Elavil: 17 people, 33.33%
  8. Periogard: 17 people, 33.33%
  9. Reglan: 17 people, 33.33%
  10. Flagyl: 17 people, 33.33%

What are other side effects people have besides Multiple sclerosis? *

  1. Weakness: 32 people, 62.75%
  2. Back Pain: 28 people, 54.90%
  3. Pain In Extremity: 25 people, 49.02%
  4. Rashes (redness): 21 people, 41.18%
  5. Acute Kidney Failure: 21 people, 41.18%
  6. Staphylococcal Infection (an infection with staphylococcus bacteria): 20 people, 39.22%
  7. Pain In Jaw: 20 people, 39.22%
  8. Temperature Intolerance (inability to go in temperature): 20 people, 39.22%
  9. Muscle Spasms (muscle contraction): 20 people, 39.22%
  10. Hypoaesthesia (reduced sense of touch or sensation): 19 people, 37.25%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 20 people, 39.22%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 33.33%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 10 people, 19.61%
  4. Arrhythmias (irregular heartbeat): 9 people, 17.65%
  5. Stress And Anxiety: 8 people, 15.69%
  6. Prostate Infection: 8 people, 15.69%
  7. Blood Testosterone Decreased: 7 people, 13.73%
  8. Neuropathy Peripheral (surface nerve damage): 7 people, 13.73%
  9. Enlarged Prostate: 7 people, 13.73%
  10. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 7 people, 13.73%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Augmentin:

Multiple sclerosis treatments and more:

How severe was Multiple sclerosis and when was it recovered:

Expand to all the drugs that have ingredients of amoxicillin; clavulanate potassium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Browse all the conditions that are associated with Multiple sclerosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium (the active ingredients of Augmentin) and Augmentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.