Avandia and Angioedema - a phase IV clinical study of FDA data

Summary:

Angioedema is reported as a side effect among people who take Avandia (rosiglitazone maleate), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Zyrtec, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Angioedema when taking Avandia. It is created by eHealthMe based on reports of 141,991 people who have side effects when taking Avandia from the FDA, and is updated regularly.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 142,155 Avandia users. Check the latest studies of Avandia.

What is Angioedema?

Angioedema (rapid swelling of the dermis) is found to be associated with 1,199 drugs and 2,100 conditions by eHealthMe. Check the latest studies of Angioedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 19, 2026

141,991 people reported to have side effects when taking Avandia.
Among them, 32 people (0.02%) have Angioedema.

Among these 32 people:

How long have people been on Avandia when they have Angioedema? *

What is the gender of people who have Angioedema when taking Avandia? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Angioedema when taking Avandia? *

What are other drugs people take besides Avandia? *

What are other side effects people have besides Angioedema? *

Heart Attack: 14 people, 43.75%
Pleural Effusion (water on the lungs): 14 people, 43.75%
Weight Increased: 13 people, 40.62%
Pneumonia: 13 people, 40.62%
Atelectasis (partial or complete collapse of the lung): 13 people, 40.62%
Bone Disorder: 13 people, 40.62%
Fall: 13 people, 40.62%
High Blood Pressure: 13 people, 40.62%
Impaired Gastric Emptying: 13 people, 40.62%
Nausea (feeling of having an urge to vomit): 13 people, 40.62%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 40.62%
Stress And Anxiety: 12 people, 37.50%
Pain In Jaw: 12 people, 37.50%
Irritable Bowel Syndrome: 2 people, 6.25%
High Blood Pressure: 2 people, 6.25%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.12%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 3.12%
Neoplasm Malignant (cancer tumour): 1 person, 3.12%
Insomnia Exacerbated (severe sleeplessness): 1 person, 3.12%
High Blood Cholesterol: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Avandia and have Angioedema?

- Check whether Angioedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Avandia:

Avandia (142,155 reports)

Angioedema treatments and more:

Angioedema (44,989 reports)

Browse all side effects of Avandia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angioedema:

Angioedema (1,199 drugs)

Browse all the conditions that are associated with Angioedema:

Angioedema (2,100 conditions)

Related publications that referenced our studies

Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .
Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on rosiglitazone maleate (the active ingredients of Avandia) and Avandia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.