Azelastine and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Azelastine (azelastine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Omeprazole, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Sciatica when taking Azelastine. It is created by eHealthMe based on reports of 17,147 people who have side effects when taking Azelastine from the FDA, and is updated regularly.

What is Azelastine?

Azelastine has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 17,397 Azelastine users. Check the latest studies of Azelastine.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,145 drugs and 1,423 conditions by eHealthMe. Check the latest studies of Sciatica.

On Jan, 25, 2026

17,147 people reported to have side effects when taking Azelastine.
Among them, 40 people (0.23%) have Sciatica.

Among these 40 people:

How long have people been on Azelastine when they have Sciatica? *

What is the gender of people who have Sciatica when taking Azelastine? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Sciatica when taking Azelastine? *

What are other drugs people take besides Azelastine? *

Vitamin D3: 12 people, 30.00%
Omeprazole: 12 people, 30.00%
Fluticasone Propionate: 11 people, 27.50%
Amlodipine: 10 people, 25.00%
Epinephrine: 10 people, 25.00%
Acetaminophen: 9 people, 22.50%
Sodium Chloride: 9 people, 22.50%
Prednisone: 9 people, 22.50%
Calcium: 8 people, 20.00%
Fish Oil: 8 people, 20.00%

What are other side effects people have besides Sciatica? *

Pain In Extremity: 14 people, 35.00%
High Blood Pressure: 12 people, 30.00%
Urinary Tract Infection: 11 people, 27.50%
Pain: 11 people, 27.50%
Back Pain: 10 people, 25.00%
Fatigue (feeling of tiredness): 8 people, 20.00%
Nausea (feeling of having an urge to vomit): 8 people, 20.00%
Joint Pain: 8 people, 20.00%
Intervertebral Disc Protrusion (spinal disc protrusion): 7 people, 17.50%
Dizziness: 7 people, 17.50%

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 12.50%
Hypersensitivity: 5 people, 12.50%
Immunodeficiency Common Variable: 5 people, 12.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 12.50%
Indigestion: 4 people, 10.00%
Pain: 4 people, 10.00%
Folate Deficiency (lack of folic acid): 4 people, 10.00%
High Blood Cholesterol: 4 people, 10.00%
Laxative Supportive Care: 4 people, 10.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Azelastine and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Azelastine:

Azelastine (17,397 reports)

Sciatica treatments and more:

Sciatica (28,508 reports)

Browse all side effects of Azelastine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,145 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,423 conditions)

Drugs similar to Azelastine and Sciatica :

How the study uses the data?

The study uses data from the FDA. It is based on azelastine hydrochloride (the active ingredients of Azelastine) and Azelastine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.