Bactrim and Brain abscess - a phase IV clinical study of FDA data

Summary:

Brain abscess is reported as a side effect among people who take Bactrim (sulfamethoxazole; trimethoprim), especially for people who are male, 30-39 old, have been taking the drug for 1 - 2 years also take Keppra, and have Graft versus host disease.

The phase IV clinical study analyzes which people have Brain abscess when taking Bactrim. It is created by eHealthMe based on reports of 86,509 people who have side effects when taking Bactrim from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Brain abscess?

Brain abscess is found to be associated with 223 drugs and 626 conditions by eHealthMe. Check the latest studies of Brain abscess.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

86,509 people reported to have side effects when taking Bactrim.
Among them, 35 people (0.04%) have Brain abscess.

Among these 35 people:

How long have people been on Bactrim when they have Brain abscess? *

What is the gender of people who have Brain abscess when taking Bactrim? *

female: 26.47 %
male: 73.53 %

What is the age of people who have Brain abscess when taking Bactrim? *

What are other drugs people take besides Bactrim? *

What are other side effects people have besides Brain abscess? *

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 13 people, 37.14%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 12 people, 34.29%
Dyspnea (difficult or laboured breathing): 6 people, 17.14%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 5 people, 14.29%
Nocardia Infection (a bacterial infection that usually starts in the lungs. it may spread to other organ systems): 5 people, 14.29%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 14.29%
Sinusitis (inflammation of sinus): 5 people, 14.29%
Headache (pain in head): 4 people, 11.43%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 4 people, 11.43%
Arrhythmias (irregular heartbeat): 4 people, 11.43%

What are the existing conditions these people have? *

Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 16 people, 45.71%
Meningoencephalitis Herpetic (inflammation of the brain and meninges by virus): 13 people, 37.14%
Hiv Infection: 6 people, 17.14%
High Blood Pressure: 4 people, 11.43%
Bacterial Infection: 3 people, 8.57%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 8.57%
Constipation: 3 people, 8.57%
Cytomegalovirus Infection: 3 people, 8.57%
Depression: 3 people, 8.57%
Diabetes: 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Bactrim and have Brain abscess?

- Check whether Brain abscess is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bactrim:

Bactrim (89,117 reports)

Brain abscess treatments and more:

Brain abscess (3,459 reports)

How severe was Brain abscess and when was it recovered:

Brain abscess in Bactrim

Expand to all the drugs that have ingredients of sulfamethoxazole; trimethoprim:

Brain abscess and drugs with ingredients of sulfamethoxazole; trimethoprim (176 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain abscess:

Brain abscess (223 drugs)

Browse all the conditions that are associated with Brain abscess:

Brain abscess (626 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim (the active ingredients of Bactrim) and Bactrim (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.